本文關鍵詞：加味黃芪湯治療氣虛型老年功能性便秘的臨床觀察　出處：《湖北中醫(yī)藥大學》2016年碩士論文　論文類型：學位論文

  更多相關文章： 加味黃芪湯 老年性 功能性便秘 氣虛型 臨床觀察

【摘要】：研究目的:本研究旨在觀察加味黃芪湯治療氣虛型老年功能性便秘的臨床療效,并從理論和臨床研究兩個方面探討加味黃芪湯治療老年功能性便秘的機制,為中醫(yī)治療氣虛型老年功能性便秘提供科學的依據(jù)。研究方法:本項研究對象均選取2014年9月-2015年12月武漢市中西醫(yī)結合醫(yī)院符合老年功能性便秘病證屬氣虛型診斷的門診病人60例,其年齡在60-80周歲之間。對患者的一般情況和病情等詳細記錄,按照隨機原則,分為治療組和對照組,剔除脫落病例,治療組26例,對照組24例,兩組患者在性別、年齡、治療前癥狀積分、病程等方面比較,無明顯的統(tǒng)計學差異(P0.05)。治療組給予口服加味黃芪湯的中藥湯劑治療,每日一劑,分早、中、晚三次于餐前30min口服;對照組單純給予西藥,莫沙必利5mg po tid,餐后30min口服,治療期間患者忌生冷刺激食物并停用其他相關藥物,療程4周,采用問卷調查形式對患者在治療后第一周、第二周、第三周、第四周的癥狀進行評分,運用SPSS 21.0軟件進行統(tǒng)計分析,評價其療效。研究結果:治療4周后,治療組26例,臨床治愈6例,顯效10例,有效8例,無效2例,總有效率92.31%;對照組24例,臨床治愈1例,顯效6例,有效11例,無效6例,總有效率78.26%,比較兩組治療后的總有效率,有明顯統(tǒng)計學差異(P0.05)。比較上述兩組在治療后的癥狀總積分,亦有明顯差異,具有統(tǒng)計學意義(P0.05),在改善癥狀方面如明顯縮短排便時間、減少排便時間間隔、改善糞便性狀、減輕排便困難程度、排便不盡感等方面治療組優(yōu)于對照組,有顯著性差異(P0.05)。治療結束停藥4周后隨訪受試者的遠期臨床療效,治療組26例,復發(fā)4例,未復發(fā)22例,復發(fā)率15.38%;對照組24例,復發(fā)15例,未復發(fā)9例,復發(fā)率62.50%,統(tǒng)計學分析后,說明這兩組之間差異有顯著統(tǒng)計學意義(P0.05),最終可以說明治療組是優(yōu)于對照組的。治療組和對照組的病人均未出現(xiàn)不良反應。研究結論:加味黃芪湯治療氣虛型老年功能性便秘療效顯著,而且在改善個別癥狀方面,如明顯縮短排便時間、減少排便時間間隔、改善糞便性狀、減輕排便困難程度和排便不盡感等方面明顯優(yōu)于對照組,隨訪的長期療效亦優(yōu)于對照組,并且未見不良反應,值得推廣于臨床應用。
[Abstract]:Objective: to observe the clinical effect of Jiawei Huangqi decoction in treating senile functional constipation with deficiency of qi, and to explore the mechanism of Jiawei Huangqi decoction in treating senile functional constipation from two aspects of theory and clinical research. To provide a scientific basis for TCM treatment of senile functional constipation with deficiency of qi. The subjects of this study were selected from September 2014 to December 2015 in Wuhan City Integrated traditional Chinese and Western Medicine Hospital in accordance with the elderly functional constipation syndrome diagnosis of Qi-deficiency type of outpatient patients 60 cases. According to the random principle, the patients were divided into treatment group and control group, excluding shedding cases, 26 cases in treatment group and 24 cases in control group. There was no significant difference in sex, age, symptom score before treatment and course of disease between the two groups (P 0.05). The treatment group was treated with oral Chinese medicine decoction of modified Astragalus decoction once a day. Early, middle and late oral administration 30 minutes before meal; The control group was given only western medicine, mosapride 5 mg po tid, oral for 30 minutes after meal. During the treatment period, the patients should not give birth to cold stimulation food and stop other related drugs. The course of treatment was 4 weeks. The symptoms of the patients in the first week, the second week, the third week and the fourth week after treatment were scored by questionnaire, and the statistical analysis was carried out with SPSS 21. 0 software. Results: after 4 weeks of treatment, 26 cases in the treatment group were clinically cured, 10 cases were markedly effective, 8 cases were effective, 2 cases were ineffective, and the total effective rate was 92.31 cases. In the control group, 1 case was clinically cured, 6 cases were markedly effective, 11 cases were effective, 6 cases were ineffective, and the total effective rate was 78.26. The total effective rate was compared between the two groups after treatment. There was significant statistical difference (P 0.05). The total symptom score of the above two groups after treatment was also significantly different (P 0.05). The treatment group was superior to the control group in improving symptoms, such as shortening defecation time, reducing defecation interval, improving fecal traits, reducing defecation difficulty and defecation feeling. There was a significant difference between the two groups (P 0.05). The long-term clinical effect of the subjects followed up 4 weeks after the end of the treatment. In the treatment group, there were 26 cases of recurrence, 4 cases of recurrence, 22 cases of no recurrence, and the recurrence rate was 15.38%. In the control group, there were 24 cases of recurrence, 15 cases of recurrence and 9 cases of non-recurrence. The recurrence rate was 62.50%. After statistical analysis, the difference between the two groups was statistically significant (P 0.05). Finally, it can be concluded that the treatment group is superior to the control group. The patients in the treatment group and the control group have no adverse reactions. Conclusion: the effect of modified Huangqi decoction on senile functional constipation of qi deficiency type is significant. And in improving individual symptoms, such as significantly shorten defecation time, reduce defecation time interval, improve fecal traits, reduce defecation difficulties and defecation feeling, and so on is obviously superior to the control group. The long-term effect of follow-up is better than that of control group, and no adverse reaction is found, so it is worth popularizing in clinical application.
【學位授予單位】：湖北中醫(yī)藥大學
【學位級別】：碩士
【學位授予年份】：2016
【分類號】：R256.35

【相似文獻】

相關期刊論文 前10條

1 趙文慧,張可彩;老年功能性便秘的臨床分析及防治[J];基層醫(yī)學論壇;2005年03期

2 瞿立武;;參歸潤通湯治療老年功能性便秘60例療效觀察[J];山西中醫(yī);2007年05期

3 黃勤偉;;綜合治療老年功能性便秘78例體會[J];基層醫(yī)學論壇;2007年23期

4 李輝;;健康教育對改善老年功能性便秘的作用[J];山西醫(yī)藥雜志(下半月刊);2011年05期

5 曹陽;賈連群;苗蘭英;謝鑫;田振國;;治秘新理論治療老年功能性便秘58例[J];遼寧中醫(yī)雜志;2012年11期

6 賈莉;;健脾行氣潤腸法治療老年功能性便秘32例[J];中國醫(yī)藥指南;2013年22期

7 商健;石冰;;便秘1號內服合大腸水療治療老年功能性便秘 22例[J];國醫(yī)論壇;2013年06期

8 王雅修;老年功能性便秘的自我調攝[J];養(yǎng)生大世界;2004年07期

9 楊鐵崢;;增水行舟法治療老年功能性便秘64例臨床療效觀察[J];中國老年學雜志;2008年10期

10 袁靜;;通腑湯治療老年功能性便秘68例[J];山西中醫(yī);2008年11期

相關會議論文 前10條

1 趙丹;;老年功能性便秘臨床觀察[A];中華中醫(yī)藥學會肛腸分會換屆會議暨便秘專題研討會論文專刊[C];2007年

2 李志;;符中柱教授治療老年功能性便秘的經(jīng)驗總結[A];貴州省中西醫(yī)結合學會肛腸學會第五屆學術交流會暨新技術新進展學習班論文匯編[C];2012年

3 蔡光先;劉柏炎;;便可通片治療老年功能性便秘39例[A];第七次全國中西醫(yī)結合虛證與老年病學術會議論文摘要集[C];2003年

4 毛麗巧;吳至久;王飛;;塞因塞用法治療老年功能性便秘的實驗研究[A];全國中醫(yī)藥防治老年病學術交流會學術論文集[C];2011年

5 唐海明;;養(yǎng)血潤下湯治療老年功能性便秘60例療效觀察[A];2012醫(yī)學前沿——中華中醫(yī)藥學會肛腸分會第十四次全國肛腸學術交流大會論文精選[C];2012年

6 唐海明;;養(yǎng)血潤下湯治療老年功能性便秘60例療效觀察[A];第十次中醫(yī)藥防治老年病學術交流會論文集[C];2012年

7 楊光;;加味四君子湯治療老年功能性便秘50例療效觀察[A];第十次中醫(yī)藥防治老年病學術交流會論文集[C];2012年

8 汪紅兵;張聲生;陳明;陶琳;張琳;朱培一;肖e，

本文編號：1357961