【摘要】：目的:初步分析國(guó)內(nèi)外口腔鱗癌的相對(duì)生存率現(xiàn)況和變化,為口腔鱗癌診治工作的研究提供基礎(chǔ)數(shù)據(jù)和初步的效果評(píng)價(jià)。方法:計(jì)算機(jī)檢索相關(guān)期刊論文(CJFD)、中國(guó)知網(wǎng)全文數(shù)據(jù)庫(kù)、萬(wàn)方全文數(shù)據(jù)庫(kù)、PUBMED數(shù)據(jù)庫(kù)等,系統(tǒng)的搜集對(duì)1970年1月至2016年12月公開發(fā)表的、以人群為基礎(chǔ)的口腔鱗癌的生存資料進(jìn)行分析,嚴(yán)格制定納入標(biāo)準(zhǔn):發(fā)病的解剖范圍包括頰粘膜、上下牙齦、磨牙后區(qū)、口底、硬腭和舌前2/3,病理分型為鱗狀細(xì)胞癌,數(shù)據(jù)均來(lái)自國(guó)家或地區(qū)的以人群為基礎(chǔ)的生存資料,以資料中的相對(duì)生存率(relative survival rate,RSR)為研究指標(biāo),對(duì)不同國(guó)家或地區(qū)間口腔鱗癌的相對(duì)生存率及其變化進(jìn)行比較。結(jié)果:初步檢索共搜集到相關(guān)文獻(xiàn)118篇。經(jīng)過(guò)篩選,將來(lái)源于全人群、提供了口腔鱗癌的觀察生存(observed survival rate,OSR)和相對(duì)生存率(relative survival rate,RSR)的文獻(xiàn)保留,對(duì)生存信息重復(fù)不全或非全人群的資料進(jìn)行刪除,最終符合納入要求的文獻(xiàn)共有49篇,其中中文文獻(xiàn)14篇,英文文獻(xiàn)35篇。通過(guò)比較我們發(fā)現(xiàn)從1970年至1999年,不同國(guó)家和地區(qū)的口腔鱗癌的相對(duì)生存率均呈現(xiàn)穩(wěn)步提高狀態(tài),2000年至今部分國(guó)家或地區(qū)的口腔鱗癌相對(duì)生存率提高緩慢或呈相對(duì)持平狀態(tài)。我國(guó)總體口腔鱗癌5年相對(duì)生存率較西方發(fā)達(dá)國(guó)家仍處于相對(duì)落后狀態(tài)。中國(guó)上海地區(qū)的口腔鱗癌5年相對(duì)生存率隨著時(shí)間的發(fā)展呈穩(wěn)步提高的趨勢(shì),到21世紀(jì)初期已達(dá)到世界先進(jìn)水平。北京、天津、臺(tái)灣等地區(qū)的口腔鱗癌相對(duì)生存率高于江蘇啟東、福建及湖南省的生存率水平。國(guó)外資料表明,歐洲和美國(guó)的口腔鱗癌相對(duì)生存率較高,而南美洲、非洲的生存率較低�？傮w上大部分國(guó)家或地區(qū)男性的口腔鱗癌相對(duì)生存率低于女性;口腔鱗癌的相對(duì)生存率與年齡的增長(zhǎng)呈負(fù)相關(guān)。結(jié)論:隨著時(shí)間的發(fā)展口腔鱗癌的生存率呈不斷提高,但整體仍處于較低的水平;我國(guó)口腔鱗癌生存率水平有所提高,部分地區(qū)接近或達(dá)到西方發(fā)達(dá)國(guó)家水平,部分地區(qū)仍有一定差距。
[Abstract]:Objective: to analyze the relative survival rate of oral squamous cell carcinoma (OSCC) at home and abroad, and to provide basic data and preliminary effect evaluation for the diagnosis and treatment of OSCC. Methods: the full text database of (CJFD), Wanfang full text database and PUBMED database were searched by computer. The data were collected and published from January 1970 to December 2016. The survival data of oral squamous cell carcinoma (OSCC) based on population were analyzed, and the inclusion criteria were strictly formulated: the anatomical range of the disease included buccal mucosa, upper and lower gingiva, posterior molar region, floor of mouth, hard palate and front of tongue, and pathological classification was squamous cell carcinoma. The relative survival rate of oral squamous cell carcinoma (OSCC) in different countries or regions was compared with the relative survival rate (relative survival rate,RSR). Results: a total of 118 literatures were preliminarily searched. After screening, the literature of oral squamous cell carcinoma (observed survival rate,OSR) and relative survival rate (relative survival rate,RSR) were preserved, and the data of incomplete or incomplete survival information were deleted. There were 49 articles, 14 in Chinese and 35 in English. From 1970 to 1999, we found that the relative survival rate of oral squamous cell carcinoma (OSCC) in different countries and regions increased steadily, and the relative survival rate of OSCC in some countries or regions has been increasing slowly or in a relatively flat state since 2000. The overall 5-year relative survival rate of oral squamous cell carcinoma in China is still relatively backward than that in western developed countries. The 5-year relative survival rate of oral squamous cell carcinoma (OSCC) in Shanghai, China, has steadily increased with the development of time, and has reached the advanced level of the world by the beginning of 21 ~ (st) century. The relative survival rate of oral squamous cell carcinoma in Beijing, Tianjin and Taiwan was higher than that in Qidong, Fujian and Hunan provinces. Foreign data show that the relative survival rate of oral squamous cell carcinoma is higher in Europe and the United States, but lower in South America and Africa. In general, the relative survival rate of male oral squamous cell carcinoma was lower than that of female, and the relative survival rate of oral squamous cell carcinoma was negatively correlated with the increase of age. Conclusion: the survival rate of oral squamous cell carcinoma (OSCC) increases with the development of time, but the overall survival rate is still at a low level. The survival rate of oral squamous cell carcinoma (OSCC) in China has been improved, some areas are close to or up to the level of western developed countries, and some areas still have a certain gap.
【學(xué)位授予單位】：青島大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R739.8

【參考文獻(xiàn)】

相關(guān)期刊論文 前10條

1 張斌;;口腔鱗狀細(xì)胞癌的表觀遺傳學(xué)研究現(xiàn)狀和進(jìn)展[J];口腔頜面外科雜志;2016年02期

2 鐘來(lái)平;孫堅(jiān);郭偉;涂文勇;竺涵光;季彤;胡永杰;李軍;葉為民;徐立群;何悅;楊雯君;王延安;任國(guó)欣;殷秋明;蔡以理;楊溪;張陳平;張志愿;;256例局部晚期口腔癌的生存分析[J];中國(guó)腫瘤臨床;2015年04期

3 何保昌;陳法;林李嵩;邱宇;蔡琳;;福建地區(qū)口腔癌預(yù)后影響因素的研究[J];福建醫(yī)科大學(xué)學(xué)報(bào);2014年03期

4 鄭榮壽;張思維;吳良有;李光琳;趙平;赫捷;陳萬(wàn)青;;中國(guó)腫瘤登記地區(qū)2008年惡性腫瘤發(fā)病和死亡分析[J];中國(guó)腫瘤;2012年01期

5 傅錦業(yè);高靜;鄭家偉;張志愿;鐘來(lái)平;項(xiàng)永兵;;口腔癌相關(guān)危險(xiǎn)因素的流行病學(xué)調(diào)查分析[J];中國(guó)口腔頜面外科雜志;2011年04期

6 陳萬(wàn)青;張思維;鄭榮壽;雷正龍;李光琳;鄒小農(nóng);趙平;;中國(guó)腫瘤登記地區(qū)2007年腫瘤發(fā)病和死亡分析[J];中國(guó)腫瘤;2011年03期

7 高靜;鄭家偉;楊馳;楊萬(wàn)水;張薇;張志愿;項(xiàng)永兵;;上海市區(qū)1973—2005年口腔惡性腫瘤發(fā)病趨勢(shì)分析[J];中國(guó)口腔頜面外科雜志;2010年01期

8 鮑萍萍;鄭瑩;王春芳;顧凱;向泳梅;吳春曉;彭鵬;金凡;;2002～2004年上海市兒童惡性腫瘤發(fā)病特征[J];中國(guó)腫瘤;2009年02期

9 鐘來(lái)平;鄭家偉;張陳平;張志愿;;口腔癌早期診斷的研究現(xiàn)狀[J];中國(guó)口腔頜面外科雜志;2007年04期

10 陳建國(guó);朱健;張永輝;;啟東市1972~2000年主要惡性腫瘤生存率分析[J];中國(guó)腫瘤;2006年09期

相關(guān)碩士學(xué)位論文 前1條

1 鄧明輝;湖南地區(qū)口腔頜面部惡性腫瘤發(fā)病情況調(diào)查分析[D];中南大學(xué);2009年

，

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