【摘要】：目的:分析卵巢子宮內膜異位癥(EMs)惡變的臨床病理特征。方法:回顧分析2011年12月至2015年12月于鄭州大學人民醫(yī)院婦科行手術治療且術后病理確診的卵巢癌患者281例,其中符合內異癥惡變診斷標準者24例(內異癥惡變組),非內異癥惡變者257例(非內異癥惡變組)。分析兩組患者的臨床組織病理學類型及FIGO分期。結果:與非內異癥惡變組相比,內異癥惡變組患者的平均年齡早、絕經前診斷比例較大,差異均有統(tǒng)計學意義(P0.05)。內異癥惡變組術前CA125值(110.27±112.62)U/ml,腹水量較少、病理類型多為透明細胞癌(45.83%)、FIGO分期早期(87.50%);非內異癥惡變組術前CA125值(1242.75±2104.28)U/ml、腹水量較多,病理類型多為漿液性腺癌(72.37%),FIGO分期晚期(74.71%);兩組比較,差異均有統(tǒng)計學意義(P均0.05)。兩組患者在癌灶單雙側及淋巴結轉移情況比較,差異均無統(tǒng)計學意義(P均0.05)。結論:卵巢內異癥惡變患者發(fā)病年齡小、腹水量少、術前CA125較低、FIGO期別早,組織病理以透明細胞癌及子宮內膜樣腺癌為主。
[Abstract]:Objective: to analyze the clinicopathological features of (EMs) malignancy in ovarian endometriosis. Methods: from December 2011 to December 2015, 281 patients with ovarian cancer treated by gynecologic surgery and confirmed by pathology in Renmin Hospital of Zhengzhou University were retrospectively analyzed. Among them, 24 cases were in accordance with the diagnostic criteria of malignant change of endometriosis (malignant change group) and 257 cases were non-malignant change group (non-malignant group). The clinicopathological types and FIGO staging of the two groups were analyzed. Results: compared with non-endometriosis group, the average age and premenopausal diagnosis of the patients were earlier and the difference was statistically significant (P0.05). The preoperative CA125 value was (110.27 鹵112.62) U / ml, the quantity of ascites was less and the pathological type was clear cell carcinoma (45.83%) early stage of Figo stage (87.50%), the preoperative CA125 value was (1242.75 鹵2104.28) U / ml, and the pathological type was serous adenocarcinoma (72.37%) late stage of Figo stage (74.71%). The difference was statistically significant (P 0.05). There was no significant difference between the two groups (P 0.05). Conclusion: the patients with malignant change of ovarian endometriosis are young in age, less in ascites, lower in CA125 before operation and earlier in Figo stage. The histopathology is mainly clear cell carcinoma and endometrial adenocarcinoma.
【作者單位】： 鄭州大學人民醫(yī)院;
【基金】：河南省醫(yī)學科技攻關計劃(No:201301007)
【分類號】：R737.31
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本文編號：2203226