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周方案紫杉醇聯(lián)合復(fù)方苦參注射液同步放化療治療局部晚期老年食管癌臨床觀察

發(fā)布時間:2018-07-22 13:04
【摘要】:目的:觀察周方案紫杉醇聯(lián)合復(fù)方苦參注射液同步放化療治療老年局部晚期食管癌的療效。方法:2012年3月—2015年3月間收治的39例局部晚期老年食管癌患者,給予紫杉醇周方案同步放療,同時應(yīng)用復(fù)方苦參注射液直至放療結(jié)束。觀察同步放化療的近期療效及毒副反應(yīng)情況。結(jié)果:紫杉醇周方案同步放化療聯(lián)合復(fù)方苦參注射液治療局部晚期老年食管癌,有效率74.4%。3級急性放射性食管炎發(fā)生率10.2%;≤70歲與70歲患者相比不良反應(yīng)差異無統(tǒng)計學(xué)意義(P㩳0.05)。結(jié)論:紫杉醇周方案聯(lián)合復(fù)方苦參注射液同步放化療治療老年局部晚期食管癌患者,取得了較好的臨床近期療效,耐受性良好。
[Abstract]:Objective: to observe the efficacy of weekly regimen paclitaxel combined with compound Sophora flavescens injection in the treatment of local advanced esophageal carcinoma in the elderly. Methods: from March 2012 to March 2015, 39 patients with locally advanced esophageal carcinoma were treated with paclitaxel week radiotherapy, and compound Sophora flavescens injection until the end of radiotherapy. To observe the short-term efficacy and side effects of concurrent radiotherapy and chemotherapy. Results: the effective rate of paclitaxel week regimen combined with compound Sophora flavescens injection in the treatment of locally advanced esophageal carcinoma in the elderly was 10.2%, and there was no significant difference in adverse reactions between patients 鈮,

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