【摘要】：背景與目的由于缺乏特異的臨床癥狀,70%的肺癌患者確診時(shí)為局部晚期或晚期,多數(shù)患者伴有實(shí)性器官轉(zhuǎn)移,不同部位轉(zhuǎn)移患者的臨床表現(xiàn)及預(yù)后不同。隨著診斷技術(shù)的發(fā)展,肺癌伴胰腺轉(zhuǎn)移似有逐漸增多趨勢(shì)。本研究針對(duì)肺癌胰腺轉(zhuǎn)移的臨床特點(diǎn)、診治、預(yù)后及生存情況進(jìn)行統(tǒng)計(jì)分析,探討肺癌胰腺轉(zhuǎn)移的相關(guān)預(yù)后因素。方法回顧性分析1996年7月-2017年6月于北京腫瘤醫(yī)院胸部腫瘤內(nèi)一科就診的35例經(jīng)病理確診的肺癌并胰腺轉(zhuǎn)移或在治療過程中出現(xiàn)胰腺轉(zhuǎn)移的患者,其中33例有完整隨訪資料。結(jié)果 35例患者中,小細(xì)胞肺癌28例(80%),腺癌3例(8.6%),鱗癌4例(11.4%)。初治時(shí)即存在胰腺轉(zhuǎn)移者21例(60%),14例治療過程中出現(xiàn)胰腺轉(zhuǎn)移(40%)。在胰腺轉(zhuǎn)移灶中,胰頭轉(zhuǎn)移者15例(42.9%),胰腺體尾部轉(zhuǎn)移者20例(57.1%),單發(fā)轉(zhuǎn)移23例(65.7%),多發(fā)轉(zhuǎn)移12例(34.3%)。肺癌胰腺轉(zhuǎn)移患者多無明顯臨床癥狀,本組病例中,僅4例患者在病程中出現(xiàn)胰腺炎癥狀。病理類型是影響肺癌胰腺轉(zhuǎn)移患者生存的獨(dú)立預(yù)后因素。結(jié)論部分晚期肺癌患者可以出現(xiàn)胰腺轉(zhuǎn)移,多見于小細(xì)胞肺癌。肺癌患者出現(xiàn)胰腺轉(zhuǎn)移,治療原則以全身化療為主的綜合治療。病理類型是影響肺癌胰腺轉(zhuǎn)移患者生存的獨(dú)立預(yù)后因素。
[Abstract]:Background and objective due to the absence of specific clinical symptoms 70% of lung cancer patients were locally advanced or advanced when diagnosed and most of the patients were accompanied with solid organ metastasis. The clinical manifestations and prognosis of patients with different sites of metastasis were different. With the development of diagnostic techniques, lung cancer with pancreatic metastasis seems to increase gradually. In this study, the clinical features, diagnosis and treatment, prognosis and survival of pancreatic metastasis of lung cancer were statistically analyzed, and the prognostic factors of pancreatic metastasis of lung cancer were discussed. Methods from July 1996 to June 2017, 35 cases of lung cancer with pancreatic metastasis or pancreatic metastasis were retrospectively analyzed. 33 of them had complete follow-up data. Results among the 35 patients, 28 (80%) were small cell lung cancer, 3 (8.6%) were adenocarcinoma, 4 (11.4%) were squamous cell carcinoma. Pancreatic metastasis was found in 21 cases (60%) and 14 cases (40%). There were 15 cases of pancreatic head metastasis (42.9%), 20 cases of pancreatic body and tail metastasis (57.1%), 23 cases of single metastasis (65.7%) and 12 cases of multiple metastasis (34.3%). There were no obvious clinical symptoms in patients with pancreatic metastasis of lung cancer, only 4 cases had pancreatitis symptoms in the course of the disease. Pathological type is an independent prognostic factor affecting the survival of patients with pancreatic metastasis from lung cancer. Conclusion Pancreatic metastasis can occur in some patients with advanced lung cancer, and is more common in small cell lung cancer. Lung cancer patients have pancreatic metastasis, the principle of treatment is systemic chemotherapy. Pathological type is an independent prognostic factor affecting the survival of patients with pancreatic metastasis from lung cancer.
【作者單位】： 中國(guó)醫(yī)學(xué)科學(xué)院腫瘤醫(yī)院腫瘤內(nèi)科;南平市人民醫(yī)院腫瘤內(nèi)科;北京大學(xué)臨床腫瘤學(xué)院北京腫瘤醫(yī)院胸部腫瘤內(nèi)一科;
【分類號(hào)】：R734.2

【相似文獻(xiàn)】

相關(guān)期刊論文 前10條

1 張希臣,顧正平;綜合治療消化系惡性腫瘤150例[J];人民軍醫(yī);2004年06期

2 郭智;;惡性腫瘤本質(zhì)的認(rèn)識(shí)和治療模式的改變[J];醫(yī)學(xué)與哲學(xué)(B);2012年01期

3 潘興國(guó);江澤琴;咸婧;張國(guó)才;駱建華;;舌癌綜合治療研究進(jìn)展[J];西南軍醫(yī);2007年06期

4 孫恒;;原發(fā)性中樞神經(jīng)系統(tǒng)淋巴瘤96例臨床分析[J];海南醫(yī)學(xué);2012年14期

5 江擁軍;尹邦良;;我國(guó)惡性腫瘤的治療現(xiàn)狀與對(duì)策[J];醫(yī)學(xué)與哲學(xué)(臨床決策論壇版);2006年12期

6 周立強(qiáng),顧大中,王奇璐,馮奉儀,黃一容,孫燕;淋巴母細(xì)胞淋巴瘤45例臨床療效分析[J];中華放射腫瘤學(xué)雜志;1998年04期

7 劉秀平;食管胃肺三重癌綜合治療1例[J];腫瘤研究與臨床;2005年03期

8 姜小華;李志強(qiáng);李長(zhǎng)江;王曉希;;四肢軟組織惡性纖維組織細(xì)胞瘤20例療效分析[J];中國(guó)煤炭工業(yè)醫(yī)學(xué)雜志;2008年11期

9 盧再鳴;劉洋;;影像學(xué)技術(shù)用于肝癌診治臨床價(jià)值[J];中國(guó)實(shí)用外科雜志;2014年08期

10 朱金蓮;袁蘇徐;王曉麗;;消化系統(tǒng)原始神經(jīng)外胚層瘤的臨床病理特征分析[J];實(shí)用癌癥雜志;2014年05期

，

本文編號(hào)：2133974