肝門部膽管癌外科治療方式的選擇及術后早期并發(fā)癥相關危險因素分析
發(fā)布時間:2018-07-18 08:38
【摘要】:[目的]探討肝門部膽管癌的臨床特征,不同分型外科治療方式的選擇,分析其術后早期并發(fā)癥的危險因素,總結該病的臨床診療經驗。[方法]回顧性分析我院2011年1月至2016年6月收治的120例肝門部膽管癌的臨床資料,根據Bisumth分型分為Ⅰ、Ⅱ、Ⅲ、Ⅳ型,每型依據治療方式的不同分為不同治療組,觀察不同治療組的生存時間及生存率,并分析手術治療組中術后并發(fā)癥發(fā)生的危險因素。[結果]①不同分型患者一般資料包括性別、年齡、體重、臨床表現(xiàn)、術前合并癥等方面比較差異均無統(tǒng)計學意義(P0.05)②對Ⅰ型及Ⅱ型患者,膽管切除的術后平均生存時間及1年、2年生存率優(yōu)于其他治療方式(包括姑息性切除、PTCD外引流、膽道支架置入),差異有統(tǒng)計學意義(P0.05)③Ⅲ型患者行半肝/擴大半肝切除術后平均生存時間及1年、2年生存率優(yōu)于膽腸吻合、PTCD外引流及膽道支架置入組,差異有統(tǒng)計學意義(P0.05)④對Ⅳ型患者,半肝/擴大半肝切除及膽道支架置入術后平均生存時間優(yōu)于膽管切除、肝段切除、手術活檢、PTCD外引流及膽道支架置入,但6種治療方式的術后1年、2年生存率比較差異無統(tǒng)計學意義(P0.05)⑤性別、術前黃疸程度、手術時間、術中出血、術中是否輸血與術后早期并發(fā)癥發(fā)生無統(tǒng)計學意義(P0.05),年齡、手術方式、術前肝功能、手術切除范圍是術后早期并發(fā)癥發(fā)生的危險因素(P0.05)。[結論]1.膽管、肝段+膽管切除術可改善Ⅰ型及Ⅱ型患者預后,提高術后生存率;故對Ⅰ型及Ⅱ型患者宜首選膽管切除術。2.Ⅲ型患者行半肝/擴大半肝切除術后平均生存時間及術后1年、2年、3年生存率高于其他治療方式。3.不論對Ⅳ型患者行何種手術,手術治療與PTCD外引流及膽道支架置入術比較,并不能改善患者預后。4.年齡、手術方式、術前肝功能、手術切除范圍是肝門部膽管癌術后早期并發(fā)癥發(fā)生的危險因素。
[Abstract]:[objective] to investigate the clinical features of hilar cholangiocarcinoma and the choice of surgical treatment methods of different types, to analyze the risk factors of early postoperative complications, and to summarize the clinical experience of diagnosis and treatment of hilar cholangiocarcinoma. [methods] the clinical data of 120 cases of hilar cholangiocarcinoma treated in our hospital from January 2011 to June 2016 were retrospectively analyzed. According to Bisumth classification, they were divided into three groups: type 鈪,
本文編號:2131355
[Abstract]:[objective] to investigate the clinical features of hilar cholangiocarcinoma and the choice of surgical treatment methods of different types, to analyze the risk factors of early postoperative complications, and to summarize the clinical experience of diagnosis and treatment of hilar cholangiocarcinoma. [methods] the clinical data of 120 cases of hilar cholangiocarcinoma treated in our hospital from January 2011 to June 2016 were retrospectively analyzed. According to Bisumth classification, they were divided into three groups: type 鈪,
本文編號:2131355
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