本文選題：多發(fā)性骨髓瘤　切入點：肺部感染　出處：《中國感染與化療雜志》2017年03期 　論文類型：期刊論文

【摘要】：目的分析多發(fā)性骨髓瘤患者發(fā)生肺部感染的臨床特點,以期為早期預防和臨床診療提供理論依據(jù)。方法回顧性分析2012年1月-2015年4月收治住院的70例多發(fā)性骨髓瘤患者的相關資料,對患者的肺部感染臨床表現(xiàn)及影像學特點、病原菌分布、感染相關因素進行分析。結果多發(fā)性骨髓瘤患者發(fā)生肺部感染時外周血白細胞計數(shù)和中性粒細胞比例可以表現(xiàn)為正常,紅細胞沉降率明顯增高,影像學提示以雙肺感染較常見,常見病原菌是以銅綠假單胞菌為主的革蘭陰性菌。發(fā)生肺部感染的易感因素主要是:粒細胞缺乏、Ⅲ期多發(fā)性骨髓瘤、合并癥。結論多發(fā)性骨髓瘤患者發(fā)生肺部感染的臨床癥狀多樣;其易感因素主要是機體免疫力低下;常見病原菌是革蘭陰性菌。在病原菌未檢出前,經(jīng)驗性使用β內酰胺類-酶抑制劑復合制劑或喹諾酮類藥物治療可有效控制感染進展。
[Abstract]:Objective to analyze the clinical features of pulmonary infection in patients with multiple myeloma. Methods the data of 70 patients with multiple myeloma admitted from January 2012 to April 2015 were analyzed retrospectively, and the clinical manifestations and imaging features of pulmonary infection were analyzed. Results the leukocyte count and neutrophil percentage in peripheral blood of multiple myeloma patients with pulmonary infection were normal and the erythrocyte sedimentation rate was significantly increased. Imaging findings showed that bipulmonary infection was more common, and the common pathogens were gram-negative bacilli with Pseudomonas aeruginosa. The main risk factors for pulmonary infection were granulocytosis, stage 鈪，

本文編號：1602230