【摘要】：目的探討Child-Turcotte-Pugh(CTP)評(píng)分與終未期肝病模型(MELD)預(yù)測(cè)晚期肝癌圍介入手術(shù)期患者生存期的優(yōu)缺點(diǎn)及互補(bǔ)性。方法收集100例晚期肝癌患者,均行TACE,術(shù)前根據(jù)MELD公式計(jì)算患者的MELD值,并同時(shí)計(jì)算CTP評(píng)分。應(yīng)用ROC曲線及其曲線下面積(AUC)分析并比較MELD、CTP評(píng)分預(yù)測(cè)患者生存時(shí)間的價(jià)值。結(jié)果采用CTP評(píng)分判斷患者TACE術(shù)前、術(shù)后3、6個(gè)月生存期的的AUC分別為0.540、0.754、0.889,而采用MELD評(píng)分時(shí)分別為0.682、0.701、0.801。2種模型判斷患者生存時(shí)間的AUC差異均有統(tǒng)計(jì)學(xué)意義(P均0.05)。結(jié)論在判斷晚期肝癌短期預(yù)后方面,MELD與CTP評(píng)分均為較好的指標(biāo)。
[Abstract]:Objective to explore the advantages and disadvantages of Child-Turcotte-Pugh (CTP) score and (MELD) model in predicting the survival time of patients with advanced liver cancer during interventional operation. Methods 100 patients with advanced liver cancer were treated with TACE.The MELD of the patients was calculated according to the MELD formula before operation and the CTP score was calculated at the same time. The ROC curve and its area under the curve were used to analyze and compare the value of (AUC) score in predicting the survival time of patients. Results the AUC of 3 and 6 months survival time of patients with TACE was 0.540 鹵0.754 鹵0.889, respectively, and that of MELD score was 0.6820.701 / 0.801.2 respectively. There were significant differences in AUC between the two models (all P 0.05). Conclusion meld and CTP scores are good indexes in judging the short-term prognosis of advanced liver cancer.
【作者單位】： 首都醫(yī)科大學(xué)附屬北京地壇醫(yī)院腫瘤介入科;
【分類(lèi)號(hào)】：R735.7;R730.55
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本文編號(hào)：2160146