本文關鍵詞：有氧運動對老年大鼠胃腸動力及血清中胃促生長素、瘦素水平的影響　出處：《中國應用生理學雜志》2016年04期 　論文類型：期刊論文

  更多相關文章： 有氧運動 老年大鼠 胃腸動力 胃促生長素 瘦素

【摘要】：目的:探討有氧運動對老年大鼠胃腸動力以及血清中胃促生長素(ghrelin)和瘦素(leptin)的影響。方法:雄性SD大鼠45只,分為青年對照組、老年對照組以及老年有氧運動組(n=15)。老年有氧運動組采用遞增負荷的方式進行8周跑臺運動。實驗過程中連續(xù)觀察并記錄各組大鼠的攝食量、體重以及行為學特征;實驗結(jié)束測定各組大鼠胃排空速率以及小腸推進比,血清Ghre-1in和Leptin。結(jié)果:與青年對照組相比,老年對照組大鼠攝食量、胃排空速率、小腸推進比、血清Ghrelin水平明顯降低,體重、體脂和Leptin水平顯著升高;與老年對照組相比,老年有氧運動組大鼠攝食量、胃排空速率、小腸推進比、血清Ghrelin水平明顯升高,體重、體脂和Leptin水平明顯降低。結(jié)論:有氧運動能促進老年大鼠食欲、提高胃腸動力、改善身體成分,其保護機制可能與血清中Ghrelin含量升高和Leptin含量降低有關。
[Abstract]:Objective: to investigate the effects of aerobic exercise on gastrointestinal motility and serum levels of ghrelin and leptin in aged rats. Methods: 45 male SD rats were enrolled in this study. Divided into youth control group. The aged control group and the old aerobic exercise group were treated with increasing load for 8 weeks. During the experiment, the feeding amount of the rats in each group was continuously observed and recorded. Weight and behavioral characteristics; At the end of the experiment, the gastric emptying rate, intestinal propulsion ratio, serum Ghre-1in and Leptin were measured. Results: compared with the young control group, the intake and gastric emptying rate of the aged rats in the control group were higher than those in the control group. Small intestinal propulsion ratio, serum Ghrelin level decreased significantly, body weight, body fat and Leptin levels increased significantly. Compared with the elderly control group, the elderly aerobic exercise group rats intake, gastric emptying rate, small intestinal propulsion ratio, serum Ghrelin level significantly increased, body weight. Conclusion: aerobic exercise can promote appetite, improve gastrointestinal motility and improve body composition in aged rats. The protective mechanism may be related to the increase of Ghrelin and the decrease of Leptin in serum.
【作者單位】： 延安大學體育學院;
【分類號】：R87
【正文快照】： 功能性消化不良(functional dyspepsia,FD)是臨床上比較常見的消化系統(tǒng)病癥,尤其在老年人群中發(fā)病率較高,關于發(fā)病機制目前尚無定論[|]。老年人隨年齡的增長消化不良酸病率明顯增高。隨著老齡化的推進和醫(yī)學對健康理念的轉(zhuǎn)變,如何改善老年人生活質(zhì)量問櫝逐漸成為人們所關注的

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