本文關鍵詞：綜合干預對運動醫(yī)學科抗菌藥物使用及醫(yī)院感染發(fā)病率的影響，由筆耕文化傳播整理發(fā)布。

綜合干預對運動醫(yī)學科抗菌藥物使用及醫(yī)院感染發(fā)病率的影響

Effect of comprehensive intervention on antimicrobial use and incidence of healthcare-associated infection in sports medicine department

[1] [2] [3] [4] [5]

YUAN Xiao-ning, REN Lin, ZHAO Xin-mao, WANG Shao-li, YANG Xue-song （Peking University Third Hospital, Beijing 100191, China）

北京大學第三醫(yī)院,北京100191

文章摘要：目的：了解綜合干預措施對某院運動醫(yī)學科住院患者抗菌藥物使用及醫(yī)院感染發(fā)病率的影響。方法回顧性分析2006年1月—2010年12月某院外科系統(tǒng)（分為運動醫(yī)學科和其他外科系統(tǒng)）住院患者抗菌藥物使用及醫(yī)院感染發(fā)生情況（干預前），2011年1月開始，運動醫(yī)學科采取“以臨床為中心、多科室合作”的綜合干預，同期其他外科系統(tǒng)未進行綜合干預；前瞻性監(jiān)測2012年1月—2013年12月該院外科系統(tǒng)住院患者抗菌藥物使用和醫(yī)院感染發(fā)病率（干預后），評價干預效果。結果干預后，運動醫(yī)學科住院患者抗菌藥物使用率及醫(yī)院感染發(fā)病率分別為55．75％、0．10％，均低于干預前（分別為95．26％、0．32％），差異均有統(tǒng)計學意義（χ^2分別為753．42、15．13，均 P ＜0．01）。干預后，其他外科系統(tǒng)住院患者抗菌藥物使用率為65．63％，低于干預前（73．79％）；醫(yī)院感染發(fā)病率為0．55％，高于干預前（0．42％），差異均有統(tǒng)計學意義（χ^2分別為251．57、19．04，均 P ＜0．01）。結論以“以臨床為中心、多科室合作”的綜合干預措施安全、有效，，可以降低運動醫(yī)學科住院患者抗菌藥物使用率，降低醫(yī)院感染發(fā)病率。

Abstr：Objective To explore the effect of comprehensive intervention measure on antimicrobial use and incidence of healthcare-associated infection（HAI）in patients in sports medicine department.Methods Antimicrobial use and incidence of HAI in hospitalized patients in the surgical departments （sports medicine department and other surgical departments）of a hospital between January 2006 and December 2010 were analyzed retrospectively（before intervention）,from January 2011, comprehensive intervention based on clinicalcentered multi-department cooperation was adopted by sports medicine department,the other surgical departments over the same period were not comprehensively intervened;antimicrobial use and incidence of HAI in patients in surgical departments between January 2012 and December 2013 were monitored prospectively （after intervention ）,effectiveness of intervention was evaluated.Results Antimicrobial use and incidence of HAI in pa-tients in sports medicine department after intervention were both lower than before intervention （55.75% vs 95.26%,χ2=753.42;0.10% vs 0.32% ,χ^2 =15.13,both P〈0.01）.Antimicrobial use in patients in other surgical departments after intervention was lower than that before intervention（65.63% vs 73.79% ,χ^2 =251.57,P〈0.01 ）;incidence of HAI was higher than that before intervention（0.55% vs 0.42% ,χ^2 =19.04,P〈0.01）.Conclusion Comprehensive in-tervention measure based on clinical-centered multi-department cooperation is safe and effective,it can reduce antimicrobial use and incidence of HAI in patients in sports medicine department.

文章關鍵詞：

Keyword：:sports medicine antimicrobial agent targeted monitor rational drug use healthcare-associated infection

課題項目：首都醫(yī)學發(fā)展科研基金（2009～3029）

  本文關鍵詞：綜合干預對運動醫(yī)學科抗菌藥物使用及醫(yī)院感染發(fā)病率的影響，由筆耕文化傳播整理發(fā)布。