本文關鍵詞： 兒童 學齡前 促性腺激素細胞 尿 黃體生成素 卵泡刺激素 社區(qū)　出處：《中國全科醫(yī)學》2017年20期 　論文類型：期刊論文

【摘要】：目的建立學齡前兒童(3~7歲)尿黃體生成素(ULH)和尿促卵泡素(UFSH)參考范圍,觀察其性別、年齡特點。方法于2015年5—7月,以江蘇省無錫市濱湖區(qū)胡埭社區(qū)3~7歲學齡前兒童為研究對象,依據(jù)2006年世界衛(wèi)生組織(WHO)生長發(fā)育標準,分別計算兒童年齡別身高Z評分(HAZ)、年齡別體質量Z評分(WAZ)和年齡別體質指數(shù)(BMI)Z評分(BAZ),3種指標均在-2SD~2SD為符合本調研入組的體格發(fā)育標準。睡前排空膀胱,留取過夜晨尿,記錄留尿時段,應用免疫化學發(fā)光法檢測ULH和UFSH,同時檢測肌酐(Cr)。結果共納入1 105例研究對象,其中3歲90例、4歲390例、5歲373例、6~7歲252例。男、女童ULH檢出率分別為5.30%(31/585)和11.54%(60/520),UFSH檢出率分別為99.83%(584/585)和99.04%(515/520)。男童和女童ULH、UFSH水平比較,差異均有統(tǒng)計學意義(Z=-3.755,P0.001;Z=-19.644,P0.001)。不同年齡女童UFSH水平比較,差異有統(tǒng)計學意義(P0.05);其中5歲、6~7歲UFSH水平均分別低于3歲、4歲(P0.05)。1 105例學齡前兒童中,-2SDHAZ≤0即長期營養(yǎng)狀況差者409例,0HAZ2SD即長期營養(yǎng)狀況好者696例。長期營養(yǎng)狀況差和長期營養(yǎng)狀況好者ULH、UFSH水平比較,差異均無統(tǒng)計學意義(Z=-1.018,P=0.309;Z=-1.114,P=0.265)。1 105例學齡前兒童中,-2SDWAZ≤0即短期營養(yǎng)狀況差者484例,0WAZ2SD即短期營養(yǎng)狀況好者621例。短期營養(yǎng)狀況差和短期營養(yǎng)狀況好者ULH水平比較,差異無統(tǒng)計學意義(Z=-0.472,P=0.637)。短期營養(yǎng)狀況差和短期營養(yǎng)狀況好者UFSH水平比較,差異有統(tǒng)計學意義(Z=-1.991,P=0.046)。結論學齡前兒童ULH檢出率低,ULH和UFSH參考范圍具有性別、年齡特點;學齡前女童UFSH隨年齡升高有下降趨勢,6歲時趨緩;短期營養(yǎng)狀況差的兒童UFSH可升高;而長期營養(yǎng)狀況不影響UFSH。
[Abstract]:Objective to establish the reference range of urinary luteinizing hormone (ULH) and urinary follicle stimulating hormone (UFSH) in preschool children, and to observe their sex and age characteristics. Methods from May to July, 2015. According to the World Health Organization (WHO) standards of growth and development in 2006, the 3-year-old 7-year-old preschool children in Hudai Community, Binhu District, Wuxi City, Jiangsu Province, were studied. The age specific height Z score, the age specific weight Z score and the age specific body mass Z score were calculated, and the age specific body mass index (BMIP Z score) and the age specific body mass index (BMIG Z score) were calculated respectively. The three indexes were -2SD-2SD as the standard of physical development. The bladder was emptied before bedtime, the overnight morning urine was taken, and the duration of urine retention was recorded. Immunochemiluminescence assay was used to detect ULH and ULH, and creatinine creatinine was detected simultaneously. Results 1 105 cases were included in this study, 90 cases were 3 years old, 90 cases were 4 390 cases, 5 years old were 373 cases. The detection rate of ULH in males and females was 5.30% 585% and 11.54% 60 / 520 respectively. The detection rate of UFSH was 99.833% 584 / 585) and 99.04515 / 5200.The levels of ULHHUFSH in boys and girls were compared. The difference was statistically significant (P 0.001). The UFSH level of girls of different ages was significantly higher than that of girls of different ages (P 0.05). The level of UFSH at the age of 5 years and 7 years was lower than that of 3 years old and 4 years old, P 0.05 and 1.105 cases of preschool children, including 409 cases whose long-term nutritional status was poor (P < 0). 0HAZ2SD was 696 cases with good long-term nutrition status, and there was no significant difference in ULHHU UFSH level between those with poor long-term nutritional status and those with good long-term nutritional status. Pu 0.309; Among 105 preschool children, 484 cases with short term nutritional status were worse than -2SDWAZ 鈮，

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