【摘要】： 玻璃體后脫離(posterior vitreous detachment, PVD)是指玻璃體后皮質與視網膜內界膜之間的分離。近視眼的PVD較為多見。準分子激光原位角膜磨鑲術(laser in situ keratomi leusis, LASIK)用于近視矯治已經在全世界廣泛開展,LASIK手術是否存在對玻璃體和視網膜的影響在臨床上越來越引起重視。傅里葉域光學相干斷層掃描(Optical coherence tomography, OCT)具有分辨率高,掃描速度快的優(yōu)點。本課題擬通過傅里葉域OCT研究近視眼患者的PVD發(fā)生情況以及LASIK手術與PVD的關系。 本文進行了以下兩個方面的研究： 一、近視眼患者的早期玻璃體后脫離 目的：評估近視眼患者早期玻璃體后脫離的發(fā)生情況。 方法：對37例(73眼)近視和近視散光的患者采用OCT及眼部B超檢查,觀察其PVD發(fā)生情況。 結果：本組患者OCT顯示早期PVD發(fā)生率為47.9%,而B超未顯示PVD。Logistic回歸分析顯示女性是發(fā)生早期PVD的危險因素。 結論：本年齡組近視眼患者部分性PVD發(fā)生率高,鼻上象限最多見。女性可能是發(fā)生早期PVD的危險因素。OCT是目前診斷早期PVD最有效的方法,可以在臨床上推廣應用。 二、近視眼患者LASIK術后玻璃體后脫離的臨床觀察 目的：評估近視眼患者行準分子激光原位角膜磨鑲術后PVD的發(fā)生情況。 方法：對37例(73眼)在我院行LASIK矯治近視和近視散光的患者采用OCT及眼部B超檢查,觀察其術前與術后第10天、第1、第3個月的PVD發(fā)生情況。 結果：術后3個月隨訪中沒有發(fā)現(xiàn)新發(fā)生的PVD及原有PVD的擴大,未觀察到玻璃體黃斑牽引綜合征、視網膜裂孔等眼后段并發(fā)癥。 結論：LASIK手術不會明顯導致PVD。LASIK手術前后用OCT動態(tài)監(jiān)測玻璃體視網膜界面,有助于及時發(fā)現(xiàn)PVD及其他病變的發(fā)生發(fā)展。
[Abstract]:The posterior vitreous detachment (PVD) refers to the separation between the posterior cortex of the vitreous and the inside of the retina. PVD of myopia is more common. Laser in situ keratomileusis (LASIK) is widely used in the treatment of myopia. Optical coherence tomography (OCT) has the advantages of high resolution and high scanning speed. This paper is to study the occurrence of PVD in patients with myopia and the relationship between LASIK and PVD by means of Fourier domain OCT. In this paper, the following two aspects are carried out The study of the patients with myopia and myopia The purpose of early vitreous detachment: to evaluate the early stage of myopia Methods: OCT and eyes were used in 37 patients (73 eyes) of myopia and myopic astigmatism. The results showed that the incidence of early PVD was 47.9% and that of B-ultrasound did not show PVD and Logistic regression. Analysis shows that women are a risk factor for early PVD. Conclusion: This age group The incidence of partial PVD in the patients with myopia is high, and the upper part of the nose The most frequently seen in the quadrant. Women may be a risk factor for early PVD. OCT is the current visit The most effective method of early-stage PVD can be applied clinically. The Clinical Observation of the Posterior Vitreous Detachment of the Patients with Myopia after LASIK Objective: To evaluate the incidence of laser in situ keratomileusis (PVD) after laser in situ keratomileusis in patients with myopia. In the follow-up of 3-month follow-up, no newly-occurring P was found in the follow-up of the 3-month follow-up. The enlargement of VD and the original PVD did not observe the complications of vitreous macular traction syndrome, retinal tears, etc. Conclusion: LASIK operation does not significantly result in PVD. LAS
【學位授予單位】：暨南大學
【學位級別】：碩士
【學位授予年份】：2010
【分類號】：R779.63

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