刺激聲間隔覺察閾測(cè)試在聽神經(jīng)病患者診斷中的臨床應(yīng)用
發(fā)布時(shí)間:2018-12-15 15:04
【摘要】:目的建立刺激聲間隔覺察測(cè)試(Random Gap Detection Test,RGDT)方法并對(duì)健聽青年人、感音性聾患者及聽神經(jīng)病患者的聽覺間隔覺察閾(Gaps-in-Noise,GIN)進(jìn)行比較和分析。方法本文主要通過在噪聲下改變間隔時(shí)間的長(zhǎng)短來檢測(cè)受試者聽覺系統(tǒng)的時(shí)間整合能力。噪聲間隔的改變采用的是一種自適應(yīng)的調(diào)節(jié)方式,即連續(xù)兩次選擇正確則增加測(cè)試難度,縮短間隔時(shí)間;若一次選擇錯(cuò)誤則降低測(cè)試難度,延長(zhǎng)間隔時(shí)間。本文選取健聽組60耳,感音性耳聾組25耳,聽神經(jīng)病組20耳,分別進(jìn)行GIN測(cè)試。結(jié)果健聽組中,女性的GIN閾值為2.95±0.86ms,男性的GIN閾值為3.10±1.15ms,男女性別無顯著性差異(P=0.6830.05,F=0.138);雙耳的測(cè)試結(jié)果為3.02±1.00ms,左耳的測(cè)試結(jié)果為3.63±1.39ms,右耳的測(cè)試結(jié)果為3.38±1.25ms,不同耳別之間沒有顯著性差異(P=0.1620.05,F=1.857)。用one-way ANOVA對(duì)聽神經(jīng)病組、感音性聾組及健聽組進(jìn)行統(tǒng)計(jì)學(xué)分析發(fā)現(xiàn)三組有顯著性差異(P=0.0000.05),其中聽神經(jīng)病組GIN閾值為29.59±19.27ms,與健聽組3.34±1.24ms相比明顯延長(zhǎng)(P=0.0000.05),感音性聾組5.34±2.78ms與健聽組有顯著性差異(P=0.0050.05),聽神經(jīng)病組與感音性聾組相比也有顯著性差異(P=0.0000.05)。結(jié)論 RG-DT是一種測(cè)試聽覺中樞系統(tǒng)時(shí)間分辨率的一項(xiàng)有效方法,可行性高,尤其對(duì)于聽神經(jīng)病患者的臨床應(yīng)用價(jià)值較高。RGDT可以為進(jìn)一步鑒別診斷聽神經(jīng)病和感音性聾提供一定參考依據(jù)。間隔覺察閾值測(cè)試可作為一項(xiàng)輔助工具補(bǔ)充并驗(yàn)證言語(yǔ)測(cè)聽的測(cè)試結(jié)果。
[Abstract]:Objective to establish the method of stimulating acoustic interval awareness test (Random Gap Detection Test,RGDT) and to compare and analyze the auditory interval perception threshold (Gaps-in-Noise,GIN) in healthy young people, patients with sensorineural hearing loss and patients with auditory neuropathy. Methods the temporal integration ability of the auditory system was measured by changing the interval under noise. The change of noise interval adopts an adaptive adjustment method, that is, the correct choice of two consecutive times increases the test difficulty, shortens the interval time, and reduces the test difficulty and prolongs the interval time if one selection error is made. 60 ears of healthy hearing group, 25 ears of sensorineural deafness group and 20 ears of auditory neuropathy group were tested by GIN. Results in the healthy hearing group, the GIN threshold of female was 2.95 鹵0.86msand that of male was 3.10 鹵1.15ms.There was no significant difference between male and female (P < 0.6830.05F = 0.138). The test results of binaural, left and right ears were 3.02 鹵1.00ms, 3.63 鹵1.39ms and 3.38 鹵1.25msrespectively. There was no significant difference between the two ears (P < 0.1620.05). The statistical analysis of auditory neuropathy group, sensorineural deafness group and healthy hearing group by one-way ANOVA showed that there were significant differences among the three groups (P0. 0000. 05). The GIN threshold of auditory neuropathy group was 29. 59 鹵19. 27ms. Compared with the healthy hearing group (3.34 鹵1.24ms), the hearing loss group (5.34 鹵2.78ms) was significantly longer than that of the healthy hearing group (P0. 005. 05), and there was a significant difference between the sensorineural hearing loss group (5. 34 鹵2.78ms) and the healthy hearing group (P0. 005. There was also significant difference between auditory neuropathy group and sensorineural deafness group (P = 0.0000.05). Conclusion RG-DT is an effective method for measuring the temporal resolution of auditory central system. Especially for the patients with auditory neuropathy, RGDT can provide some references for the further differential diagnosis of auditory neuropathy and sensorineural deafness. Interval awareness threshold test can be used as an auxiliary tool to supplement and verify the results of speech audiometry.
【作者單位】: 解放軍總醫(yī)院耳鼻咽喉頭頸外科-耳內(nèi)科解放軍耳鼻咽喉研究所;解放軍總醫(yī)院耳鼻咽喉頭頸外科—耳內(nèi)科解放軍耳鼻咽喉研究所;
【基金】:國(guó)家重大科學(xué)研究計(jì)劃項(xiàng)目(2014CB943001) 國(guó)家自然基金重大國(guó)際合作項(xiàng)目(81120108009) 全軍“十二五”重點(diǎn)項(xiàng)目(BWS11J026)聯(lián)合資助
【分類號(hào)】:R764
[Abstract]:Objective to establish the method of stimulating acoustic interval awareness test (Random Gap Detection Test,RGDT) and to compare and analyze the auditory interval perception threshold (Gaps-in-Noise,GIN) in healthy young people, patients with sensorineural hearing loss and patients with auditory neuropathy. Methods the temporal integration ability of the auditory system was measured by changing the interval under noise. The change of noise interval adopts an adaptive adjustment method, that is, the correct choice of two consecutive times increases the test difficulty, shortens the interval time, and reduces the test difficulty and prolongs the interval time if one selection error is made. 60 ears of healthy hearing group, 25 ears of sensorineural deafness group and 20 ears of auditory neuropathy group were tested by GIN. Results in the healthy hearing group, the GIN threshold of female was 2.95 鹵0.86msand that of male was 3.10 鹵1.15ms.There was no significant difference between male and female (P < 0.6830.05F = 0.138). The test results of binaural, left and right ears were 3.02 鹵1.00ms, 3.63 鹵1.39ms and 3.38 鹵1.25msrespectively. There was no significant difference between the two ears (P < 0.1620.05). The statistical analysis of auditory neuropathy group, sensorineural deafness group and healthy hearing group by one-way ANOVA showed that there were significant differences among the three groups (P0. 0000. 05). The GIN threshold of auditory neuropathy group was 29. 59 鹵19. 27ms. Compared with the healthy hearing group (3.34 鹵1.24ms), the hearing loss group (5.34 鹵2.78ms) was significantly longer than that of the healthy hearing group (P0. 005. 05), and there was a significant difference between the sensorineural hearing loss group (5. 34 鹵2.78ms) and the healthy hearing group (P0. 005. There was also significant difference between auditory neuropathy group and sensorineural deafness group (P = 0.0000.05). Conclusion RG-DT is an effective method for measuring the temporal resolution of auditory central system. Especially for the patients with auditory neuropathy, RGDT can provide some references for the further differential diagnosis of auditory neuropathy and sensorineural deafness. Interval awareness threshold test can be used as an auxiliary tool to supplement and verify the results of speech audiometry.
【作者單位】: 解放軍總醫(yī)院耳鼻咽喉頭頸外科-耳內(nèi)科解放軍耳鼻咽喉研究所;解放軍總醫(yī)院耳鼻咽喉頭頸外科—耳內(nèi)科解放軍耳鼻咽喉研究所;
【基金】:國(guó)家重大科學(xué)研究計(jì)劃項(xiàng)目(2014CB943001) 國(guó)家自然基金重大國(guó)際合作項(xiàng)目(81120108009) 全軍“十二五”重點(diǎn)項(xiàng)目(BWS11J026)聯(lián)合資助
【分類號(hào)】:R764
【參考文獻(xiàn)】
相關(guān)期刊論文 前9條
1 王秋菊;;聽神經(jīng)病的臨床及基礎(chǔ)研究[J];國(guó)際耳鼻咽喉頭頸外科雜志;2006年06期
2 馬麗濤;李娜;孫R,
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