【摘要】：近十余年來,我國原發(fā)性開角型青光眼(以下簡稱開青)患病率逐年上升,由0.29%上升到2.6%,一躍成為最重要的不可逆性致盲眼病。由于對開青眼壓升高及視神經(jīng)損害的機制認識不清,缺乏可行的篩查及有效的干預技術(shù),其致盲率遠高于發(fā)達國家8%的平均水平。王寧利教授所領(lǐng)導的項目組從回答開青眼壓升高和視神經(jīng)損害的關(guān)鍵科學問題入手,以解決開青篩查和監(jiān)測的關(guān)鍵技術(shù)和設備為突破口,在闡明開青發(fā)病機制的基礎上建立了基于機制的新分類體系,并在新理論、新分類基礎上創(chuàng)建了新的開青篩查、診斷、監(jiān)測和治療技術(shù),在全國范圍內(nèi)推廣應用。覆蓋人群1.2億,實際受益患者320萬人,減少因開青致盲約32萬人,開青致盲率由15%下降到5%,減少開青致殘約64萬人,致殘率由30%下降到15%。
[Abstract]:In recent ten years, the prevalence rate of primary open-angle glaucoma (hereinafter referred to as Kaiqing) has increased year by year, from 0.29% to 2.6%, which has become the most important irreversible blindness. The blindness rate was much higher than the average of 8% in developed countries due to the lack of clear understanding of the mechanism of elevated intraocular pressure and optic nerve damage and the lack of feasible screening and effective intervention techniques. The project team led by Professor Wang Ningli began by answering the key scientific questions of elevated intraocular pressure and optic nerve damage, taking the key technology and equipment for screening and monitoring Kaiqing as a breakthrough. A new classification system based on mechanism was established on the basis of expounding the pathogenesis of Kaiqing disease, and a new screening, diagnosis, monitoring and treatment technology was established on the basis of new theory and new classification, which was popularized and applied in the whole country. 120 million people were covered, 3.2 million patients were actually benefited, about 320000 people were reduced to blindness caused by opening green, the rate of blindness caused by youth was reduced from 15% to 5, and the disability rate was reduced from 30% to 15%, and 640000 cases were reduced from 30% to 15%.
【作者單位】： 首都醫(yī)科大學附屬北京同仁醫(yī)院北京市眼科研究所;
【基金】：國家自然科學基金(81271005,81300767)~~
【分類號】：R775.2

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本文編號：2338717