【摘要】：目的:通過(guò)分析紅花注射液治療前后突發(fā)性聾患者聽(tīng)閾的改變和血清超氧化物歧化酶(SOD)、丙二醛(MDA)的變化,探討其對(duì)突發(fā)性聾的治療機(jī)制。方法:40例突發(fā)性聾患者隨機(jī)分為Ⅰ組(紅花組)和Ⅱ組(無(wú)紅花組),檢測(cè)治療前后純音聽(tīng)力、血清MDA、SOD值變化。另選取聽(tīng)力均屬于正常范圍者25例作為對(duì)照組。結(jié)果:Ⅰ組治療總有效率高于Ⅱ組(χ2=4.183,P0.05)。治療前Ⅰ、Ⅱ組突發(fā)性聾患者血清SOD值低于對(duì)照組(t值分別為-6.495和-6.945,均P0.05),MDA值高于對(duì)照組(t值分別為12.061和10.592,均P0.05)。Ⅰ組治療后SOD值較治療前明顯增高(t=6.665,P0.05),MDA值較治療前明顯降低(t=-16.497,P0.05)。Ⅱ組治療后SOD值和MDA值與治療前比較變化不明顯(t值分別為1.556和-0.395,均P0.05)。結(jié)論:紅花注射液能清除體內(nèi)的氧自由基,促進(jìn)聽(tīng)力的恢復(fù)。
[Abstract]:Objective: to investigate the mechanism of safflower injection in the treatment of sudden deafness by analyzing the changes of hearing threshold and serum superoxide dismutase (SOD),) malondialdehyde (MDA) in patients with sudden deafness before and after treatment. Methods 40 patients with sudden deafness were randomly divided into two groups: group 鈪，

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