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  本文選題：光學相干斷層成像 + 激光光凝術(shù)�。� 參考：《新疆醫(yī)科大學》2014年碩士論文

【摘要】：目的：通過光學相干斷層成像(Optical Coherence Tomography,OCT)評價眼底全視網(wǎng)膜激光光凝術(shù)(Panretinal Photocoagulation,PRP)聯(lián)合玻璃體腔內(nèi)注射曲安奈德(Triamcinolone Acetonide,TA)治療糖尿病性黃斑水腫(Diabetic Macular Edema,DME)的療效。方法：對新疆醫(yī)科大學第五附屬醫(yī)院2012年3月-2013年10月采用眼底視網(wǎng)膜激光光凝術(shù)聯(lián)合玻璃體腔內(nèi)注射曲安奈德治療糖尿病性黃斑水腫的56例病例進行回顧性分析。結(jié)果：(1)視力：術(shù)后1周、1個月、3個月、6個月的視力與用藥前相比均有統(tǒng)計學意義(P0.05)。(2)眼壓：術(shù)后1周、1月、3月、6月與術(shù)前比較均有統(tǒng)計學意義(0.05)。其中術(shù)后1周、1月、3月眼壓升高明顯,6月時開始下降。(3)黃斑中心凹視網(wǎng)膜厚度：治療后較治療前明顯降低,術(shù)后1周、1月、3月、6月之間差異具有統(tǒng)計學意義(P0.05),其中第6月時開始緩慢上升,較治療前仍有顯著差異。(4)黃斑部總體積：較術(shù)前相比,患者術(shù)后黃斑區(qū)總體積減小,術(shù)后1周、1月、3月、6月較術(shù)前均具有統(tǒng)計學意義(P0.05)。(5)黃斑部平均視網(wǎng)膜厚度：治療后較術(shù)前顯著降低,術(shù)前與術(shù)后1周、1月、3月、6月之間差異具有統(tǒng)計學意義(P0.05)。(6)最佳矯正視力(BCVA)與黃斑中心凹視網(wǎng)膜厚度、黃斑部容積及黃斑區(qū)平均視網(wǎng)膜厚度的關系：BCVA分別與黃斑中心凹視網(wǎng)膜厚度、黃斑部總體積、黃斑部平均視網(wǎng)膜厚度具有負相關性。結(jié)論：聯(lián)合治療DME的治療方法在短期內(nèi)可以很好的減輕黃斑水腫,減少黃斑中心凹視網(wǎng)膜厚度、減少黃斑部總體積及黃斑部平均視網(wǎng)膜厚度,從而可以提高視力。
[Abstract]:Objective: to evaluate the efficacy of panretinal photocoagulation combined with intravitreal injection of triamcinolone acetonide (TIA) in the treatment of diabetic macular edema (DM) by optical coherence tomography (Oct). Methods: 56 cases of diabetic macular edema treated by retinal laser photocoagulation combined with intravitreal injection of triamcinolone acetonide from March 2012 to October 2013 in the Fifth affiliated Hospital of Xinjiang Medical University were retrospectively analyzed. Results the visual acuity of 1 week, 1 month, 3 months and 6 months after operation was significantly higher than that before treatment (P 0.05). IOP: 1 week, 1 month, 3 months, 6 months after operation, there was significant difference in IOP between 1 week, 1 month, 3 months, 6 months and preoperation. The intraocular pressure increased significantly at 1 week, 1 month and 3 months postoperatively, and began to decrease at 6 months.) Retinal thickness of central fovea of macula: after treatment, it was significantly lower than that before treatment. The difference was statistically significant between 1 week, 1 month, 3 months and 6 months after the operation, in which the volume of macular area began to rise slowly at the 6th month, and was significantly different from that before treatment. 1 week, 1 month, 3 months and 6 months postoperatively, there were significant differences in the mean retinal thickness of macular region between before and after treatment (P 0.05, P 0.05, P < 0.05). After treatment, the mean retinal thickness was significantly lower than that before treatment. The difference between preoperative and postoperative 1 week, 1 month, 3 months and 6 months was statistically significant (P 0.05) BCVA) and macular central foveal retinal thickness. The relationship between macular volume and mean retinal thickness of macular area was negatively correlated with macular central foveal retinal thickness, total macular volume and mean macular retinal thickness, respectively. Conclusion: the combined treatment of DME can reduce macular edema, macular central fovea retinal thickness, macular total volume and mean macular retinal thickness in a short period of time, so as to improve visual acuity.
【學位授予單位】：新疆醫(yī)科大學
【學位級別】：碩士
【學位授予年份】：2014
【分類號】：R774.1;R587.2

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本文編號：1970746