本文選題：鼻咽腫瘤 + 遠(yuǎn)處轉(zhuǎn)移�。� 參考：《廣東醫(yī)學(xué)》2014年05期

【摘要】：目的分析304例首程治療的無(wú)遠(yuǎn)處轉(zhuǎn)移鼻咽癌患者治療后遠(yuǎn)處轉(zhuǎn)移部位和時(shí)間間隔,探討鼻咽癌遠(yuǎn)處轉(zhuǎn)移模式。方法收集排除遠(yuǎn)處轉(zhuǎn)移及病理確診后行根治性治療鼻咽癌患者1 338例。治療后其中304例隨訪發(fā)現(xiàn)遠(yuǎn)處轉(zhuǎn)移。采用Kaplan-Meier法計(jì)算總生存率。結(jié)果鼻咽癌患者遠(yuǎn)處轉(zhuǎn)移占治療失敗患者總數(shù)的65.2%;中位間隔時(shí)間為18個(gè)月。Ⅰ、Ⅱ、Ⅲ和Ⅳ期遠(yuǎn)處轉(zhuǎn)移例數(shù)分別占各期總數(shù)的0、12.6%、23.2%和31.5%。T1、T2、T3、T4和N0、N1、N2、N3期轉(zhuǎn)移例數(shù)分別占各期總數(shù)的20.1%、20.5%、27%、24.6%和11.3%、22.6%、23.7%、41.1%。遠(yuǎn)處轉(zhuǎn)移最常見(jiàn)部位為骨、肝、肺。出現(xiàn)在治療后1、2、3、4年內(nèi)分別占5年遠(yuǎn)處轉(zhuǎn)移總數(shù)的35.5%、63.8%、83.2%、94.4%。結(jié)論遠(yuǎn)處轉(zhuǎn)移為鼻咽癌治療失敗最主要原因且多數(shù)發(fā)生在治療后3年內(nèi)。臨床分期尤其是N分期的嚴(yán)重程度與遠(yuǎn)處轉(zhuǎn)移密切相關(guān)。
[Abstract]:Objective to analyze the location and time interval of distant metastasis in 304 patients with nasopharyngeal carcinoma without distant metastasis after first course treatment, and to explore the pattern of distant metastasis of nasopharyngeal carcinoma. Methods 1 338 patients with nasopharyngeal carcinoma were treated with radical therapy after distant metastasis and pathological diagnosis. After treatment, 304 cases were followed up with distant metastasis. The overall survival rate was calculated by Kaplan-Meier method. Results distant metastasis accounted for 65.2% of the total number of patients with nasopharyngeal carcinoma and the median interval was 18 months. The number of distant metastases in stages 鈪，

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