本文選題：光學相干斷層掃描 + 增強深度成像　； 參考：《眼科新進展》2015年10期

【摘要】：目的研究青少年屈光不正患者的脈絡(luò)膜厚度的特點及其與屈光度、眼軸長度等因素的相關(guān)性。方法隨機對在屈光門診完成驗光的5~18歲屈光不正青少年進行了脈絡(luò)膜厚度和眼軸長度的測量。最終51例102眼患者納入研究。使用海德堡頻域OCT的增強深度成像模式對每眼進行經(jīng)黃斑中心凹水平方向線性掃描。分別測量該掃描線上5個位點的脈絡(luò)膜厚度。應(yīng)用IOL master測量眼軸長度。結(jié)果 51例患者年齡為(10.04±2.78)歲,屈光度為(-1.61±1.82)D,眼軸長度為(24.14±1.14)mm。掃描線上脈絡(luò)膜厚度由顳側(cè)向鼻側(cè)逐漸變薄。屈光度與眼軸長度呈顯著負相關(guān)(R2=0.562),各位點的脈絡(luò)膜厚度均與屈光度呈顯著正相關(guān)(P0.01),與眼軸長度則呈顯著負相關(guān)(P0.05),中心凹鼻側(cè)1 mm處相關(guān)性最高。中心凹下的脈絡(luò)膜厚度與年齡呈顯著負相關(guān)。結(jié)論后極部脈絡(luò)膜厚度的改變可能在屈光度及眼軸長度改變相關(guān)的病理生理變化中起到重要的作用。
[Abstract]:Objective to study the characteristics of choroidal thickness in juvenile ametropia and its correlation with diopter and axial length. Methods the choroidal thickness and axial length were measured at random among 518 year old dioptric adolescents who completed optometry at refractive clinic. Finally, 51 patients with 102 eyes were included in the study. Heidelberg frequency domain OCT enhanced depth imaging mode was used to scan each eye in the horizontal direction through macular fovea. The choroidal thickness of 5 sites on the scan line was measured. The length of eye axis was measured by IOL master. Results the age of 51 patients was 10.04 鹵2.78 years old, the diopter was 1.61 鹵1.82D, the length of eye axis was 24.14 鹵1.14mm. The thickness of the choroid on the scan line gradually thinned from the temporal side to the nasal side. There was a significant negative correlation between diopter and axial length. There was a significant positive correlation between choroidal thickness and diopter (P 0.01), a significant negative correlation with axial length (P 0.05), and the highest correlation was found at 1 mm of central fovea. The thickness of choroid in subcentral fovea was negatively correlated with age. Conclusion the change of choroidal thickness at the posterior pole may play an important role in the pathophysiological changes of diopter and axial length.
【作者單位】： 暨南大學第二臨床醫(yī)學院;深圳市人民醫(yī)院眼科;深圳市眼科醫(yī)院 深圳市眼科學重點實驗室;暨南大學附屬深圳眼科醫(yī)院;
【分類號】：R778.1

【共引文獻】

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本文編號：1837946