本文選題：Pentacam + 裂隙燈光學(xué)相干斷層成像術(shù)　； 參考：《第三軍醫(yī)大學(xué)學(xué)報(bào)》2014年12期

【摘要】：目的評(píng)估Pentacam與SL-OCT測(cè)量原發(fā)性閉角型青光眼(primary angle-closure glaucoma,PACG)應(yīng)用激光周邊虹膜切開(kāi)術(shù)(laser peripheral iridoplasty,LPI)手術(shù)前后中央前房深度(center anterior chamber depth,CACD)的差異性、相關(guān)性和一致性。方法在我院眼科門(mén)診篩查PACG患者中符合行LPI術(shù)的病例共58例(58眼),應(yīng)用眼前節(jié)分析系統(tǒng)Pentacam和裂隙燈光學(xué)相干斷層成像術(shù)(slit-lamp-adapted optical coherence tomography,SL-OCT)分別對(duì)PACG患者進(jìn)行CACD測(cè)量,分別記錄LPI術(shù)前,術(shù)后1 d、1周、1個(gè)月參數(shù)。結(jié)果 Pentacam測(cè)得PACG患者LPI術(shù)前,術(shù)后1 d、1周及1個(gè)月的CACD分別為(1.60±0.31)、(1.65±0.28)、(1.62±0.30)、(1.61±0.31)mm。SL-OCT測(cè)量LPI術(shù)前,術(shù)后1 d、1周及1個(gè)月的CACD分別為(1.70±0.30)、(1.73±0.30)、(1.71±0.31)、(1.72±0.31)mm。2種測(cè)量方式LPI術(shù)前與術(shù)后各時(shí)間比較,差異均無(wú)統(tǒng)計(jì)學(xué)意義(P0.05);而2種測(cè)量方式之間相比較,術(shù)前及術(shù)后相同時(shí)間點(diǎn)差異均具有統(tǒng)計(jì)學(xué)意義(P0.01)。Pentacam與SL-OCT測(cè)量PACG患者LPI術(shù)前,術(shù)后1 d、1周及1個(gè)月的CACD值均存在顯著相關(guān)關(guān)系(r=0.929,P0.001;r=0.962,P0.001;r=0.961,P0.001;r=0.951,P0.001)。通過(guò)Bland-Altman分析方法,Pentacam與SL-OCT測(cè)量LPI術(shù)前,術(shù)后1 d、1周及1個(gè)月CACD差異的95%置信界限分別為-0.33~0.12、-0.29~0.08、-0.25~0.08、-0.26~0.07 mm。結(jié)論 Pentacam與SL-OCT測(cè)量PACG患者LPI術(shù)后CACD具有高度一致性和相關(guān)性,二者均可作為青光眼臨床篩查的輔助檢查方式,為患者提供了有效的無(wú)創(chuàng)且可量化的便捷檢查。
[Abstract]:Objective to evaluate the difference, correlation and consistency of central anterior chamber depth anterior chamber before and after laser peripheral irido iridoplasty with Pentacam and SL-OCT measurements of primary angle-closure glaucoma (angle-closure glaucoma). Methods 58 cases (58 eyes) of PACG patients who were in accordance with LPI in our hospital were examined by Pentacam and slit lamp optical coherence tomography (slit-lamp-adapted optical coherence tomographySL-OCTT). The CACD of PACG patients was recorded before LPI. The parameters were 1 week and 1 month after operation. Results the CACD of LPI in PACG patients was 1.60 鹵0.31 and 1.65 鹵0.28 鹵1.61 鹵0.31)mm.SL-OCT before 1 day and 1 month after PACG, respectively. The CACD of 1 week and 1 month after operation were 1.70 鹵0.301.73 鹵0.30 鹵1.71 鹵0.31 鹵1.72 鹵0.31)mm.2, respectively, compared with each time before and after LPI, the CACD of 1 week and 1 month after operation were 1.70 鹵0.301.73 鹵0.30 鹵1.71 鹵0.31 鹵1.72 鹵1.72 鹵0.31)mm.2, respectively, and the CACD of 1 week and 1 month after operation were 1.70 鹵0.301.73 鹵0.30 鹵1.71 鹵1.72 鹵1.72 鹵0.31)mm.2, respectively. There was no significant difference between the two measurement methods (P 0.05), but there were significant differences between the two methods before and after operation (P 0.01). Pentacam was significantly correlated with the value of CACD before LPI 1 week and 1 month after SL-OCT in patients with PACG. There was a significant correlation between the CACD values of 0. 929 P 0. 001 P 0. 962% P 0. 001 ~ 0. 961g P 0. 001 P 0. 001 P 0. 001 P 0. 001 P 0. 001 P 0. 001 P 0. 001 P 0. 001 P 0. 001 P 0. 001 P 0. 001 P 0. 001 P 0. 001 P 0. 001 P 0. 001 P 0. 001 P 0. 001 and 1 month after the operation. The 95% confidence limit of CACD difference at 1 week and 1 month after LPI was measured by Bland-Altman and SL-OCT. The 95% confidence limit of CACD difference was -0.33 ~ 0.12 ~ (-0.29) ~ 0.08 ~ (-0.25) ~ 0.08 ~ 0.26 ~ 0.07 mm 路min ~ (-1), respectively. Conclusion Pentacam and SL-OCT have high consistency and correlation in the measurement of CACD after LPI in PACG patients. Both of them can be used as auxiliary examination for clinical screening of glaucoma and provide effective noninvasive and quantifiable convenient examination for patients.
【作者單位】： 第三軍醫(yī)大學(xué)大坪醫(yī)院野戰(zhàn)外科研究所眼科;
【分類號(hào)】：R779.63

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