【摘要】：目的探討心外膜脂肪組織(Epicardial adipose tissue,EAT)厚度是否與冠狀動脈病變Gensini評分、Syntax評分相關(guān);并進一步評價其是否可作為預(yù)測嚴(yán)重的、復(fù)雜的冠狀動脈狹窄的預(yù)測因素。方法將102名符合納入標(biāo)準(zhǔn)的患者根據(jù)冠狀動脈造影(coronary arteriography,CAG)結(jié)果分2組,正常冠脈組、冠心病病變組(≥1冠狀動脈病變≥50%)。同期使用經(jīng)胸超聲心動圖測量EAT厚度,并回顧CAG圖像得出Gensini評分、Syntax評分。結(jié)果EAT厚度在冠脈正常組為3.89±0.2mm,冠心病病變組為6.19±1.19mm(P0.001)。結(jié)果顯示EAT的厚度分別為5 mm、5-7mm和7 mm時,Gensini評分分別為:7.21±7.73,37.80±29.55和62.77±27.26;Syntax評分分別為:7.13±7.70,19.71±7.27和24.95±4.31。EAT的厚度與Gensini評分(r=0.621;P0.001)、Syntax評分(r=0.689;P0.001)正相關(guān),與冠心病病變復(fù)雜程度正相關(guān)。ROC曲線顯示,EAT厚度提示冠脈病變較高復(fù)雜程度的最佳診斷界限值為5.55mm(曲線下面積0.834,95%可信區(qū)間(CI),0.755—0.913;P0.001)。敏感性為90.9%,特異性為67.7%。結(jié)論心外膜脂肪組織厚度與冠狀動脈狹窄的復(fù)雜程度評分,Gensini評分、Syntax評分相關(guān),它可作為預(yù)測冠狀動脈狹窄復(fù)雜病變的預(yù)測因素。
[Abstract]:Objective to investigate whether the thickness of epicardial adipose tissue (Epicardial adipose tissue,EAT) is correlated with the Gensini score and Syntax score of coronary artery disease, and to evaluate whether the thickness of epicardial adipose tissue can be used as a predictor of severe and complicated coronary artery stenosis. Methods according to the results of coronary angiography (coronary arteriography,CAG), 102 patients with coronary artery disease were divided into two groups: normal coronary artery group and coronary artery disease group (鈮，

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