急性主動脈夾層院內(nèi)死亡的危險因素
發(fā)布時間:2018-03-28 14:26
本文選題:急性主動脈夾層 切入點:院內(nèi)死亡率 出處:《中華高血壓雜志》2017年04期
【摘要】:目的研究急性主動脈夾層(AAD)患者臨床特點及院內(nèi)死亡危險因素,建立風(fēng)險預(yù)測模型。方法回顧分析2004年1月至2016年5月武警總醫(yī)院住院治療的AAD患者病史資料,應(yīng)用單因素及多因素Logistic回歸分析確定患者院內(nèi)死亡的獨立危險因素,建立風(fēng)險預(yù)測模型,并通過Hosmer-Lemeshow擬合優(yōu)度檢驗和受試者工作特征(ROC)曲線下面積判斷該模型對AAD患者院內(nèi)死亡的預(yù)測能力。結(jié)果所有196例AAD患者中36例患者住院期間死亡,院內(nèi)死亡率為18.4%。多因素Logistic回歸分析顯示,AAD院內(nèi)死亡的獨立危險因素包括:年齡≥65歲(OR=4.57,P=0.010),低血壓(OR=9.58,P=0.001),急性腎損傷(OR=11.42,P=0.001),缺血性并發(fā)癥(OR=6.35,P=0.001),神經(jīng)系統(tǒng)癥狀(OR=7.60,P=0.020),A型夾層(OR=7.59,P=0.001),Hosmer-Lemeshow擬合優(yōu)度檢驗P=0.18,ROC曲線下面積為0.92。結(jié)論年齡≥65歲、低血壓、急性腎損傷、缺血性并發(fā)癥、神經(jīng)系統(tǒng)癥狀及A型夾層為AAD患者院內(nèi)死亡的獨立危險因素。
[Abstract]:Objective to study the clinical characteristics and risk factors of hospital death in patients with acute aortic dissection (AAD) and to establish a risk prediction model. Methods the history of AAD patients hospitalized in Armed Police General Hospital from January 2004 to May 2016 was analyzed retrospectively. Univariate and multivariate Logistic regression analysis was used to determine the independent risk factors of hospital mortality, and a risk prediction model was established. The predictive ability of the model to hospital death of AAD patients was evaluated by Hosmer-Lemeshow goodness test and area under the operating characteristics curve. Results 36 out of 196 AAD patients died in hospital. The hospital mortality rate was 18.44.The independent risk factors for hospital mortality by multivariate Logistic regression analysis were as follows: the age 鈮,
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