本文關(guān)鍵詞： 慢性充血性心力衰竭 左室射血分?jǐn)?shù) 心臟變時(shí)功能不良 心臟變時(shí)性指數(shù) 運(yùn)動(dòng)試驗(yàn) CV事件　出處：《廣東醫(yī)學(xué)》2017年S1期 　論文類型：期刊論文

【摘要】：目的探索慢性充血性心力衰竭(CHF)患者左室射血分?jǐn)?shù)(EF)與心臟變時(shí)功能不良的相關(guān)性。方法入選CHF患者180例,根據(jù)其EF值分為3組,A組60例(EF值范圍:30%~35%),B組61例(EF值范圍:36%~40%),C組59例(EF值范圍:41%~45%),入選時(shí)患者常規(guī)檢測心臟彩超,如有心肌梗死或腦卒中病史的患者,常規(guī)檢測心臟CT或腦部CT。入選后隨訪12個(gè)月,分別在入組后5 d內(nèi)、第6個(gè)月末、第12個(gè)月末對(duì)患者行運(yùn)動(dòng)試驗(yàn)(患者配戴動(dòng)態(tài)心電圖儀,在平直走廊盡可能快地步行3 min),然后測定心臟變時(shí)性指數(shù)(CRI),記錄隨訪期心血管不良事件發(fā)生情況。結(jié)果 A、B、C三組在入組后5 d內(nèi)的CRI值分別為0.62±0.14、0.66±0.18、0.70±0.16,組間差異無統(tǒng)計(jì)學(xué)意義(P0.05);第6個(gè)月末分別為0.66±0.15、0.70±0.19、0.77±0.24,A組與C組差異有統(tǒng)計(jì)學(xué)意義(P0.05),B組與A、C組差異無統(tǒng)計(jì)學(xué)意義(P0.05);第12個(gè)月末分別為0.69±0.26、0.76±0.21、0.86±0.20,組間差異有統(tǒng)計(jì)學(xué)意義(P0.05);隨訪期心血管不良事件發(fā)生率分別為15.0%、8.2%、6.8%,A組與B、C兩組差異有統(tǒng)計(jì)學(xué)意義(P0.05),B組與C組差異無統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論在CHF患者中,EF值與心臟變時(shí)功能不良呈負(fù)相關(guān),在CHF患者完善CRI檢測,有利于預(yù)測患者預(yù)后,及早治療,降低患者風(fēng)險(xiǎn)。
[Abstract]:Objective to investigate the relationship between left ventricular ejection fraction (EFF) and chronotropic dysfunction in patients with chronic congestive heart failure (CHF). According to their EF values, they were divided into three groups: group A, 60 cases with EF value range 30: 30, and group B, 61 cases with EF range of 61 cases with EF value of: 36, 40, 40, group C, 59 cases with EF value in the range of: 41and 4545. The patients were routinely examined with echocardiography, if they had a history of myocardial infarction or cerebral apoplexy. The patients were followed up for 12 months after routine detection of cardiac CT or brain CT. Exercise tests were performed on the patients within 5 days, 6 months, 12 months after admission (patients wore dynamic electrocardiograph). Walk 3 mins as fast as possible in the flat and straight corridor, then measure the cardiac chronotropic index (CRI) and record the occurrence of cardiovascular adverse events during the follow-up period. Results the CRI values of the three groups were 0.62 鹵0.140.66 鹵0.180.70 鹵0.16 within 5 days after entering the group respectively. There was no statistical difference between the three groups. There was no significant difference between group A and group C at the end of the sixth month (P 0.05) and 0.69 鹵0.260.76 鹵0.21 鹵0.86 鹵0.20 at the end of 12 months, and there was significant difference between group A and C in the occurrence of cardiovascular adverse events during follow-up period (P 0.05), and the difference between group A and group C was statistically significant (P 0.05) at the end of the sixth month, and there was no significant difference between group A and group C at the end of the sixth month (P 0.05), and the difference was 0.69 鹵0.260.76 鹵0.21 鹵0.86 鹵0.20 at the end of 12 months, and there was significant difference between the two groups in the occurrence of cardiovascular adverse events in the follow-up period. There was significant difference between group A and group B (P 0.05) and group C (P 0.05). Conclusion there is a negative correlation between EF and cardiac dysfunction in patients with CHF. Improving CRI detection in patients with CHF is helpful to predict prognosis, early treatment and reduce the risk of patients.
【作者單位】： 茂名市中醫(yī)院特診病區(qū);
【分類號(hào)】：R541.61

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