【摘要】：目的:研究血液濾過(guò)聯(lián)合持續(xù)區(qū)域動(dòng)脈灌流對(duì)重癥急性胰腺炎治療效果的影響。方法:選擇2011年9月至2013年11月我院接診的202例重癥急性胰腺炎患者進(jìn)行研究,隨機(jī)分為觀察組和對(duì)照組。觀察組100例患者,采用血液濾過(guò)配合持續(xù)區(qū)域動(dòng)脈灌流治療。對(duì)照組102例患者,采用傳統(tǒng)的方法進(jìn)行治療。比較兩組患者治療前后各項(xiàng)指標(biāo)。結(jié)果:治療3~7 d后,觀察組的體溫低于對(duì)照組,更接近于正常體溫(t=10.699 9,P0.000 1);觀察組患者的心率、呼吸、血漿淀粉酶、丙氨酸氨基轉(zhuǎn)移酶、尿素氮、肌酐和APACHEⅡ評(píng)分、白細(xì)胞、中性粒細(xì)胞比例均明顯改善,其與對(duì)照組相比差異有統(tǒng)計(jì)學(xué)意義(P0.05),更接近于正常值。觀察組的住院時(shí)間、腹痛緩解時(shí)間、腹脹緩解時(shí)間、腸道功能恢復(fù)時(shí)間也短于對(duì)照組,觀察組的器官衰竭總例數(shù)少于對(duì)照組(P0.05)。結(jié)論:血液濾過(guò)配合持續(xù)區(qū)域動(dòng)脈灌流治療重癥急性胰腺炎能有效減輕患者的過(guò)度炎癥反應(yīng),能提高重癥急性胰腺炎的治愈率與改善患者的預(yù)后,效果良好,值得臨床推廣。
[Abstract]:Objective: to study the effect of hemofiltration combined with continuous regional arterial perfusion on the treatment of severe acute pancreatitis. Methods: from September 2011 to November 2013, 202 patients with severe acute pancreatitis were randomly divided into observation group and control group. In the observation group, 100 patients were treated with hemofiltration combined with continuous regional arterial perfusion. 102 patients in the control group were treated with traditional methods. The indexes of the two groups before and after treatment were compared. Results: after 3 and 7 days of treatment, the body temperature of the observation group was lower than that of the control group, which was closer to the normal body temperature (t 鈮，

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