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梗阻性黃疸患者經(jīng)皮經(jīng)肝膽道引流術(shù)后膽道感染相關(guān)因素研究

發(fā)布時(shí)間:2019-04-20 12:33
【摘要】:目的研究梗阻性黃疸患者經(jīng)皮經(jīng)肝膽道引流術(shù)(PTCD)術(shù)后發(fā)生膽道感染的相關(guān)因素。方法選取2014年10月-2016年10月在醫(yī)院接受治療的120例梗阻性黃疸患者為研究對象,采用PTCD治療,觀察比較并分析患者術(shù)后發(fā)生膽道感染的相關(guān)因素。結(jié)果 120例梗阻性黃疸患者術(shù)后發(fā)生膽道感染22例,感染率18.33%;對120例梗阻性黃疸患者基本資料進(jìn)行研究,結(jié)果顯示年齡、術(shù)前黃疸天數(shù)、術(shù)前卡氏評(píng)分(KPS)、引流量、術(shù)前谷丙轉(zhuǎn)氨酶(ALT)、堿性磷酸酶(ALP)、總膽紅素(TBIL)等生化指標(biāo)與術(shù)后出現(xiàn)膽道感染密切相關(guān),差異有統(tǒng)計(jì)學(xué)意義(P0.05);其中術(shù)前黃疸天數(shù)過長、術(shù)前ALP指標(biāo)水平過高是造成術(shù)后膽道感染的危險(xiǎn)因素,術(shù)后引流良好是術(shù)后膽道感染的保護(hù)因素;性別、梗阻部位及引流方法均不影響術(shù)后膽道感染的發(fā)生,差異無統(tǒng)計(jì)學(xué)意義。結(jié)論梗阻性黃疸患者術(shù)后膽道感染的相關(guān)因素包括年齡、術(shù)前黃疸天數(shù)、術(shù)前KPS評(píng)分、引流量、術(shù)前ALT、ALP、TBIL等,其中造成術(shù)后膽道感染的危險(xiǎn)因素主要包括術(shù)前黃疸天數(shù)過長、術(shù)前ALP指標(biāo)水平過高,有效的引流能夠促進(jìn)手術(shù)的順利實(shí)施,繼而降低術(shù)后膽道感染發(fā)生率,屬于術(shù)后膽道感染的保護(hù)因素。
[Abstract]:Objective to study the related factors of biliary tract infection after percutaneous transhepatic biliary drainage (PTCD) in patients with obstructive jaundice. Methods 120 patients with obstructive jaundice who were treated in hospital from October 2014 to October 2016 were selected and treated with PTCD. The related factors of postoperative biliary tract infection were compared and analyzed. Results there were 22 cases of biliary tract infection after operation in 120 cases of obstructive jaundice, the infection rate was 18.33%. The basic data of 120 patients with obstructive jaundice were studied. The results showed that age, days of preoperative jaundice, preoperative (KPS), drainage, preoperative glutamic pyruvic transaminase (ALT), alkaline phosphatase (ALP),. Total bilirubin (TBIL) and other biochemical indicators were closely related to postoperative biliary tract infection, the difference was statistically significant (P0.05); The long days of preoperative jaundice and the high level of preoperative ALP were the risk factors of postoperative biliary tract infection, and the good drainage after operation was the protective factor of postoperative biliary tract infection. Sex, site of obstruction and drainage method did not affect the occurrence of postoperative biliary tract infection, and there was no significant difference between the two groups. Conclusion the related factors of postoperative biliary tract infection in patients with obstructive jaundice include age, days of preoperative jaundice, preoperative KPS score, drainage volume, preoperative ALT,ALP,TBIL, and so on. The risk factors of postoperative biliary tract infection include long days of preoperative jaundice and high level of preoperative ALP. Effective drainage can promote the smooth implementation of the operation and then reduce the incidence of postoperative biliary tract infection, and the risk factors for postoperative biliary tract infection include long days before operation and high level of postoperative biliary tract infection. It belongs to the protective factor of postoperative biliary tract infection.
【作者單位】: 寧波市第二醫(yī)院肝膽胰科;
【分類號(hào)】:R575

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