本文選題：胃食管反流病 + 牙周疾病��； 參考：《新疆醫(yī)科大學》2017年碩士論文

【摘要】：目的:探討胃食管反流病(Gastroesophageal reflux disease,GERD)的流行病學特點及與牙周疾病的之間的關系及相關危險因素,為其臨床預防及治療提供依據。方法:對于2015年4月到2016年4月就診于我院的80名GERD患者和71名正常人進行GERD相關問卷和牙周疾病檢查,牙周檢查以社區(qū)牙周指數(Community periodontal index,CPI)和附著喪失(Attachment loss,AL)作為診斷標準,進行單因素分析和多因素Logistic回歸分析。結果:GERD患者與對照組比較,年齡,性別,吸煙比列等指標之間差異無統計學意義(P0.05),而民族,BMI指數,等指標之間有統計學差異(P0.05),GERD患者中維吾爾族患者發(fā)生牙周疾病比漢族患者多,(Body Mass Index,,BMI)BMI指數、GERD患者牙周炎患病率、在GERD患者中牙周炎嚴重程度均顯著高于對照組,通過Logistics回歸分析可知年齡是牙周炎的危險因素,非GERD是牙周疾病的保護因素。結論:可以認為與吸煙,年齡等相關危險因素一樣,GERD疾病是牙周疾病的危險因素之一,其診治需要多科的共同協作,早期診斷胃食管反流病并通過改變生活方式和藥物來抑制酸反流,對預防牙周疾病極為重要。口腔以及胃腸都是人體消化系統當中的組成部分,在臨床上針對上述兩種疾病開展治療以及預后的時候,都會綜合兩者間的影響,通過綜合考慮能夠更好的制定出科學的治療方法,因此在疾病發(fā)生當中有著一定的關聯性,但是這一猜測還需要更深入的研究和證實。
[Abstract]:Objective: to investigate the epidemiological characteristics of gastroesophageal reflux disease (GERD) and the relationship between GERD and periodontal disease, and to provide evidence for its clinical prevention and treatment.Methods: from April 2015 to April 2016, 80 patients with GERD and 71 normal controls were examined with GERD related questionnaire and periodontal disease. The periodontal examination was based on the community periodontal index (CPI) and attachment loss (attachment).Univariate analysis and multivariate Logistic regression analysis were performed.Results compared with the control group, there was no significant difference in age, sex and smoking ratio between the two groups, but there was no significant difference in BMI index between the two groups.There was statistical difference between the two indexes. The prevalence of periodontitis in Uygur patients was higher than that in Han patients, and the severity of periodontitis in GERD patients was significantly higher than that in the control group, and the prevalence of periodontitis was significantly higher in Uygur patients than in the Han nationality patients, and the prevalence of periodontitis in the patients with GERD was significantly higher than that in the controls.Age was the risk factor of periodontitis and non-GERD was the protective factor of periodontal disease by Logistics regression analysis.Conclusion: GERD is one of the risk factors of periodontal disease, and the diagnosis and treatment of GERD need the cooperation of many departments.Early diagnosis of gastroesophageal reflux disease and inhibition of acid reflux by changing lifestyle and drugs are very important to prevent periodontal disease.The oral cavity and the gastrointestinal tract are part of the human digestive system, and the clinical treatment and prognosis of these two diseases will combine the effects of the two.Scientific treatment methods can be better formulated through comprehensive consideration, so there is a certain correlation in the occurrence of disease, but this speculation still needs to be further studied and confirmed.
【學位授予單位】：新疆醫(yī)科大學
【學位級別】：碩士
【學位授予年份】：2017
【分類號】：R571

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