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CCR7/p-ERK1/2/VEGF signaling promotes retinal neovasculariza

發(fā)布時(shí)間:2022-09-28 13:10
  AIM: To investigate the role of CCR7/p-ERK1/2/VEGF signaling in the mouse model of oxygen-induced retinopathy(OIR). METHODS: Neonatal C57BL/6J mice were evenly randomized into four groups: normoxia, OIR, OIR control(treated with scramble si RNA), and OIR treated(treated with CCR7 siRNA). Normoxia group was not specially handled. Postnatal day 7(P7) mice in the OIR group were exposed to 75%±5% oxygen for 5d(P7-P12) and then maintained under normoxic conditions for 5d(P12-P17). Mice in the OIR con... 

【文章頁(yè)數(shù)】:8 頁(yè)

【文章目錄】:
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION


【參考文獻(xiàn)】:
期刊論文
[1]CCR7和VEGF在缺氧時(shí)視網(wǎng)膜血管內(nèi)皮細(xì)胞中的表達(dá)及意義[J]. 底煜,陳曉隆,王愛媛.  國(guó)際眼科雜志. 2015(03)



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