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鼻咽癌IMRT治療前采用CBCT復(fù)位的臨床研究

發(fā)布時(shí)間:2018-11-10 13:36
【摘要】:目的探索初治鼻咽癌患者調(diào)強(qiáng)放療(IMRT)治療前行錐形束CT(CBCT)復(fù)位的可行性。方法納入23例鼻咽癌IMRT治療患者,以定位中心坐標(biāo)原點(diǎn)作為計(jì)劃中心點(diǎn)制訂帶CBCT驗(yàn)證的逆向調(diào)強(qiáng)放射治療計(jì)劃,治療前采用CBCT復(fù)位,并于第2、3次放療前行CBCT掃描,對3次的配準(zhǔn)數(shù)據(jù)進(jìn)行匯總分析。結(jié)果復(fù)位CBCT任一方向絕對值小于或等于3mm占89.9%(62/69),5mm占98.6%(68/69),各方向偏差值為(0.6±2.1)mm;第2、3次CBCT任一方向絕對值小于或等于3mm占92.8%(128/138),5mm占99.3%(137/138),各方向偏差值為(0.4±2.0)mm;兩組數(shù)據(jù)比較差異無統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論以定位中心坐標(biāo)原點(diǎn)作為計(jì)劃中心點(diǎn)制定鼻咽癌IMRT計(jì)劃,治療前采用CBCT復(fù)位,直觀方便切實(shí)可行。
[Abstract]:Objective to explore the feasibility of conical bundle CT (CBCT) reduction before intensity-modulated radiotherapy (IMRT) in nasopharyngeal carcinoma. Methods 23 patients with nasopharyngeal carcinoma (NPC) treated with IMRT were included. The plan of inverse intensity modulated radiotherapy with CBCT validation was made with the origin of central coordinate as the planning center. CBCT was repositioned before treatment, and CBCT scanning was performed before the 2nd 3rd radiotherapy. The registration data for 3 times are summarized and analyzed. Results the absolute value of CBCT in either direction was 89.9% (62 / 69), 5mm was 98.6% (68 / 69), the deviation of each direction was (0.6 鹵2.1) mm;. The absolute value of CBCT in any direction was less than 92.8% (128 / 138) in any direction and 99.3% (137 / 138) in 5mm. There was no significant difference between the two groups in the deviation of each direction (0.4 鹵2.0) mm; (P0.05). Conclusion the IMRT plan of nasopharyngeal carcinoma is made by using the origin of positioning center coordinate as the center of plan, and CBCT reduction is used before treatment, which is intuitionistic, convenient and practical.
【作者單位】: 全軍腫瘤診治研究所/第三軍醫(yī)大學(xué)新橋醫(yī)院腫瘤科;
【分類號】:R739.63

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