上石疽的辯證分型及臨床病理研究
發(fā)布時間:2018-09-10 17:18
【摘要】:目的:通過組織病理學手段探討鼻咽癌頸淋巴結的轉移情況與大小關系。 方法: 收集我院1992年11月~2011年5月未治的鼻咽癌且行頸部淋巴結活檢術(或全頸/局部頸淋巴結清掃術)病例30例,分析術后病理記錄的淋巴結轉移情況與其最大徑、最短徑等之間的關系。 結果: 1.病理分型結果 30份術后標本,按照WHO2003年鼻咽癌鏡下分型,其中非角化型癌30例。 2.淋巴結的大小與轉移的情況 全組共收集淋巴結55枚,經(jīng)病理核實陽性淋巴結46個,轉移率83.6%(46/55)淋巴結的分布以Ⅱ~Ⅴ區(qū)為主:Ⅰ區(qū)淋巴結共6枚,轉移率為100%,而Ⅱ~Ⅴ淋巴結49枚(因無完整影像資料,無法區(qū)分具體分區(qū)),陽性淋巴結40個,轉移率81.6%(40/49),無咽后淋巴結;全組淋巴結,短徑2~45mm,中位數(shù):23.5mm,其中短徑lOmm的淋巴結有24枚,病理顯示轉移淋巴結19個,轉移率79.2%(19/24),而短徑≥10mm的淋巴結有31個,陽性淋巴結27個,轉移率87.1%(27/31),短徑≥10mm組和≥8mm組分別作為診斷標準所得全組淋巴結的敏感性、特異性、準確性、陽性預測值及陰性預測值分別為:58.7%、55.6%、58.2%、87.1%、20.8%和69.6%、55.6%、67.3%、88.9%、26.3%,短徑≥8mm組各指標均優(yōu)于短徑≥10mm組,但差異無統(tǒng)計學意義(P0.05) 3.簇集狀淋巴結轉移情況 4組呈簇集淋巴結共18枚,轉移淋巴結15個,轉移率83.3%,其中短徑≥8mm的淋巴結4個,轉移率100%(4/4),而短徑8mmm的淋巴結14個,轉移淋巴結11個,轉移率78.6%(11/14),其中短徑分布在5~8mm的淋巴結數(shù)目為0,短徑≥8mm和8mm組淋巴結所得敏感性、特異性、準確性、陽性預測值及陰性預測值分別是26.7%、100%、38.9%、100%、21.4%和26.7%、0%、61.1%、78.6%、0%,兩者之間P0.05。 結論: 鼻咽癌頸淋巴結轉移率高,這可能于淋巴結取樣標本多來源于頸部淋巴結摘除活檢術有關,其中短徑10mm的淋巴結也存在較高的轉移率,需臨床醫(yī)師重視,把短徑≥8mm作為簇集狀淋巴結的診斷標準是合理的。
[Abstract]:Objective: to investigate the relationship between metastasis and size of cervical lymph nodes in nasopharyngeal carcinoma by histopathological methods. Methods: from November 1992 to May 2011, 30 patients with nasopharyngeal carcinoma underwent cervical lymph node biopsy (or total neck / local neck lymph node dissection). To analyze the relationship between lymph node metastasis and its maximum and shortest diameter. Results: 1. Pathological classification results of 30 postoperative specimens, according to the WHO2003 age of nasopharyngeal carcinoma classification under the microscope, including 30 cases of non-keratinized carcinoma. 2. The size and metastasis of lymph nodes were collected from 55 lymph nodes in the whole group. 46 positive lymph nodes were confirmed by pathology. The metastatic rate was 83.6% (46 / 55). The distribution of lymph nodes was mainly in 鈪,
本文編號:2235102
[Abstract]:Objective: to investigate the relationship between metastasis and size of cervical lymph nodes in nasopharyngeal carcinoma by histopathological methods. Methods: from November 1992 to May 2011, 30 patients with nasopharyngeal carcinoma underwent cervical lymph node biopsy (or total neck / local neck lymph node dissection). To analyze the relationship between lymph node metastasis and its maximum and shortest diameter. Results: 1. Pathological classification results of 30 postoperative specimens, according to the WHO2003 age of nasopharyngeal carcinoma classification under the microscope, including 30 cases of non-keratinized carcinoma. 2. The size and metastasis of lymph nodes were collected from 55 lymph nodes in the whole group. 46 positive lymph nodes were confirmed by pathology. The metastatic rate was 83.6% (46 / 55). The distribution of lymph nodes was mainly in 鈪,
本文編號:2235102
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