【摘要】：精準定性、定量評估眼前節(jié)及后節(jié)的影像學技術,不僅對多種眼病的準確診斷至關重要,同時也可為治療方案、手術方式以及隨訪提供重要參考依據。作為一種分辨率高、非接觸無創(chuàng)的成像技術,光學相干斷層掃描(optical coherence tomography,OCT)已成為玻璃體視網膜相關疾病必不可少的輔助檢查工具。近幾年提出的掃頻光學相干斷層掃描成像(swept-source OCT,SS-OCT)技術,具備掃描速度提高及穿透深度加深的優(yōu)點,同時運用不同成像系統(tǒng)可獲得眼部不同層次結構精準的成像。新型的SS-OCT成像技術可用于評估眼前節(jié)結構,如角膜移植術后角膜瓣、前房參數等檢查,也加深了對玻璃體視網膜相關疾病如糖尿病性黃斑病變、眼底新生血管的轉歸和黃斑毛細血管擴張等疾病病理形態(tài)改變的認識。同時,運用玻璃體增強成像(enhanced vitreous visualization,EVV)、分層掃描(En face SS-OCT)和SS-OCT血管造影等成像系統(tǒng),可為眼底相關疾病,如玻璃體后脫離、視網膜前膜、視網膜脫離、糖尿病牽拉性視網膜脫離等手術適應證制定最佳的治療方案并協助術后隨訪。此外,該技術還為多種眼部疾病如青光眼、眼腫瘤的病理形態(tài)學觀察提供精準的微結構成像圖。本文主要對SS-OCT的技術原理及臨床應用進展等方面進行綜述。
[Abstract]:Accurate qualitative and quantitative evaluation of the imaging techniques of anterior segment and posterior segment is not only very important for the accurate diagnosis of various eye diseases, but also provides an important reference for the treatment, operation and follow-up. As a high-resolution, non-contact non-invasive imaging technique, optical coherence tomography (Oct) has become an indispensable auxiliary examination tool for vitreoretinal diseases. In recent years, swept-source optical coherence tomography (SS-OCT) has the advantages of increasing scanning speed and deepening penetration depth. At the same time, different imaging systems can be used to obtain accurate imaging of different ocular layers. New SS-OCT imaging techniques can be used to evaluate the structure of anterior segment, such as corneal flap after corneal transplantation, parameters of anterior chamber and so on. It also deepens vitreoretinal diseases such as diabetic macular disease. Recognition of fundus neovascularization and macular capillary dilatation. At the same time, imaging systems such as vitreous enhancement imaging (enhanced vitreous visualization (EVV), layered scanning (En face SS-OCT) and SS-OCT angiography can be used as fundus related diseases, such as posterior vitreous detachment, preretinal membrane, retinal detachment, and so on. The optimal treatment for diabetic traction retinal detachment and other surgical indications was established and postoperative follow-up was assisted. In addition, the technique provides accurate microstructural imaging for various ocular diseases such as glaucoma and pathomorphology of eye tumors. This article reviews the technical principle and clinical application of SS-OCT.
【作者單位】： 南華大學附屬第一醫(yī)院眼科;南昌大學第一附屬醫(yī)院眼科;
【基金】：國家自然科學基金資助(編號81660158、81160118、81160148、81460092、81400372) 江西省遠航工程(編號:2014022) 江西省自然科學基金重大項目(編號:2016ACB21017) 江西省自然科學青年基金(編號:20151BAB215016) 江西省科技支撐計劃項目(編號:20151BBG70223) 江西省衛(wèi)計委科技計劃面上項目(編號:20175116、20155204)~~
【分類號】：R770.4

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