發(fā)布時間：2018-03-24 07:13

  本文選題：黏液調(diào)節(jié)劑　切入點：兒童　出處：《聽力學及言語疾病雜志》2017年06期

【摘要】：目的觀察桉檸蒎腸溶軟膠囊預防兒童急性中耳炎鼓室積液的效果。方法 2013年4月至2016年9月發(fā)病48小時內(nèi)就診的341例(497耳)6~12歲兒童急性中耳炎(非化膿性)患兒隨機分為實驗組(172例46耳)和對照組(169例251耳),對照組給予1%苯酚甘油滴耳,糠酸莫米松噴鼻劑噴鼻,每日一次,實驗組在同對照組治療基礎上口服桉檸蒎腸溶軟膠囊半個月;于發(fā)病第7日和第14日復診,比較兩組癥狀和體征變化,對照組7日復診時明確鼓室積液的患兒加用桉檸蒎腸溶軟膠囊。結果7日復診時對照組發(fā)生鼓室積液110例(170耳)(65.09%,110/169),實驗組發(fā)生鼓室積液51例(70耳)(29.65%,51/172),前者高于后者(P0.01);14日復診時,對照組仍有鼓室積液41例(66耳)(24.26%,41/169),實驗組鼓室積液32例(36耳)(18.60%,32/172),前者高于后者(P0.05)。14日復診時對照組7日復診確診為鼓室積液的110患兒中規(guī)律服藥的75例患兒中鼓室積液消失54例(60耳)(72.0%,54/75),未規(guī)律服藥的35例患兒中鼓室積液消失15例(22耳)(42.86%,15/35),差異有統(tǒng)計學意義(P0.01)。結論兒童急性中耳炎患者發(fā)病后口服桉檸蒎腸溶軟膠囊能夠有效降低鼓室積液的發(fā)生率,發(fā)生鼓室積液后加用該藥可促進積液的排出。
[Abstract]:Objective to observe the effect of eucalyptus lime-pine-dissolving soft capsule on the prevention of tympanic effusion in children with acute otitis media. Methods 341 cases of acute otitis media (non-suppurative) in children aged 6 to 12 years old from April 2013 to September 2016 within 48 hours of onset were studied. Children were randomly divided into experimental group (n = 172, n = 46) and control group (n = 169, n = 251). Momethasone furoate nasal spray, once a day, the experimental group took eucalyptus pinpinenteric-soluble soft capsule for half a month on the basis of the same treatment as the control group, and the symptoms and signs of the two groups were compared on the 7th and 14th day after the onset of the disease. The children in the control group were treated with eucalyptus pinpinol enteric-soluble soft capsule on the 7th day. Results on the 7th day, 110 cases of tympanic effusion occurred in the control group (65.09%), and 51 cases in the experimental group had hydrotympanic effusion (29.65%), which was higher than that in the latter group (P 0.01); on the 14th day, the patients in the control group had 65.09% of tympanic effusion, and 51 cases in the experimental group had hydrotympanic effusion (29.65%), which was higher than that in the latter group (P 0.01). 41 cases of tympanic effusion were still found in the control group (41 cases, 66 ears) and 24.26% (41 / 169), while in the experimental group, 32 cases (36 ears) of tympanic effusion were 18.60% 32 / 172, the former was higher than that of the latter (P0.05%). On the 14th day, 75 cases of 110 children who were diagnosed with tympanic effusion on the 7th day in the control group were given regular medication of tympanic effusion. There were 54 cases of disappearance of 60 ears or 72.0% of 75% of the total, and of 35 cases of irregular drug taking, the tympanic effusion disappeared in 15 cases. The difference was statistically significant (P 0.01). Conclusion after the onset of acute otitis media in children, the incidence of tympanic effusion can be effectively reduced by taking eucalyptus lime enteric soft capsule after the onset of acute otitis media. After tympanic effusion occurs, adding this medicine can promote the efflux of effusion.
【作者單位】： 大連市中心醫(yī)院耳鼻咽喉頭頸外科;
【分類號】：R764.21

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