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結腸癌合并腸梗阻患者急診術后切口感染的病原學與危險因素分析

發(fā)布時間:2018-04-10 05:16

  本文選題:結腸癌 切入點:腸梗阻 出處:《中華醫(yī)院感染學雜志》2017年05期


【摘要】:目的結腸癌合并腸梗阻急診術后切口感染率較高,嚴重影響患者術后康復,本文旨在分析結腸癌合并腸梗阻患者急診術后切口感染的病原學和危險因素,為臨床防治結腸癌合并腸梗阻急診術后感染提供參考。方法回顧性收集2011年1月-2016年6月醫(yī)院收治的結腸癌合并腸梗阻的患者189例,所有患者均行急診結腸癌切除術,觀察切口感染率,分析患者的病原學和臨床特征,并分析切口感染的危險因素。結果 35例患者發(fā)生切口感染,共培養(yǎng)出48株細菌,其中革蘭陰性菌占62.50%,革蘭陽性菌占37.50%;合并糖尿病的患者切口感染率顯著增高(44.44%vs14.20%,P=0.000),手術時間≥150min的患者切口感染率顯著增高(24.07%vs 11.11%,P=0.013),術前白細胞≥109/L的患者切口感染率顯著增高(26.56%vs14.40%,P=0.042);C-反應蛋白≥10mg/L的患者切口感染率顯著增加(22.88%vs11.27%,P=0.047);白蛋白30g/L的患者切口感染率顯著增加(29.09%vs14.18%,P=0.017);多因素logistic回歸分析顯示糖尿病、術前白細胞≥109/L、C-反應蛋白≥10mg/L和白蛋白30g/L是結腸癌合并腸梗阻患者術后切口感染的危險因素。結論結腸癌合并腸梗阻患者急診術后以革蘭陰性菌常見,糖尿病、白細胞增高、C-反應蛋白增高和白蛋白降低是結腸癌合并腸梗阻患者急診術后切口感染的危險因素。
[Abstract]:Objective to analyze the etiology and risk factors of incision infection in colon cancer complicated with intestinal obstruction after emergency operation.To provide reference for clinical prevention and treatment of postoperative infection of colon cancer complicated with intestinal obstruction.Methods 189 patients with colonic cancer complicated with intestinal obstruction were collected retrospectively from January 2011 to June 2016. All patients underwent emergency colon cancer resection. The incision infection rate was observed, and the etiology and clinical features of the patients were analyzed.The risk factors of incision infection were analyzed.Results the infection of incision occurred in 35 patients and 48 strains of bacteria were cultured.The rate of incision infection in patients with diabetes mellitus was significantly higher than that in patients with diabetes mellitus (44.44 vs 14.20) 0.000, and the infection rate of incisions in patients with operation time 鈮,

本文編號:1729820

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