發(fā)布時間：2018-03-27 15:11

  本文選題：異位骨化　切入點：髖臼骨折　出處：《中國矯形外科雜志》2017年10期

【摘要】：[目的]探討吲哚美辛在預防髖臼骨折術后異位骨化中的作用。[方法]回顧性分析本院自2009年1月~2012年1月收治的120例采用Kocher-Langenbeck入路治療的髖臼骨折病例,將上述患者隨機分為兩組,無藥物組患者60例,術后無任何藥物干預,吲哚美辛組患者60例,術后1d開始口服吲哚美辛,25 mg/次,3次/d,持續(xù)4周;術后門診隨訪X線片并記錄異位骨化發(fā)生情況,隨訪時間最短6個月,最長18個月。[結果]在所有的患者中,異位骨化發(fā)生率為49%,其中Brooker Ⅰ級16例,Ⅱ級18例,Ⅲ級15例,Ⅳ級10例,18例患者有癥狀,4例需要再次手術。吲哚美辛組與無藥物組相比,輕度異位骨化發(fā)生率明顯降低,但重度異位骨化的發(fā)生率無明顯差異。[結論]髖臼骨折術后應用吲哚美辛并不能有效預防重度異位骨化的發(fā)生,應提高醫(yī)生手術技巧,降低發(fā)生率。
[Abstract]:[objective] to investigate the role of indomethacin in preventing heterotopic ossification after acetabular fracture. [methods] 120 cases of acetabular fracture treated by Kocher-Langenbeck approach from January 2009 to January 2012 were retrospectively analyzed. The above patients were randomly divided into two groups: 60 patients without drugs and 60 patients with indomethacin after operation. The patients in the indomethacin group received 25 mg/ / d of indomethacin orally for 4 weeks. The incidence of ectopic ossification was 49.Results the incidence of ectopic ossification was 49,16 Brooker 鈪，

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