本文選題：關(guān)節(jié)成形術(shù)　切入點：置換　出處：《中國組織工程研究》2017年23期

【摘要】：背景:單髁關(guān)節(jié)置換術(shù)近年來發(fā)展迅速,全球范圍內(nèi)手術(shù)量明顯增加。但目前尚無關(guān)于單髁假體的系統(tǒng)綜述。目的:對單髁假體的演變發(fā)展歷史和現(xiàn)狀進(jìn)行綜述,討論目前常用單髁假體的分類、特點和臨床效果,為臨床提供指導(dǎo)。?方法:檢索Pub Med和萬方數(shù)據(jù)庫與單髁假體和單髁臨床效果相關(guān)的文章。共檢索到文獻(xiàn)177篇,排除重復(fù)性研究,納入35篇,加上四大關(guān)節(jié)登記中心的年度報告4篇,總計納入39篇文獻(xiàn)進(jìn)行綜述。結(jié)果與結(jié)論:(1)單髁假體歷經(jīng)60多年的曲折發(fā)展已經(jīng)逐漸成熟,文獻(xiàn)報道的10年假體生存率已經(jīng)超過90%;(2)目前主流假體主要是以O(shè)xford 3為代表的活動平臺和以ZUK和Link為代表的固定平臺。兩類假體在長期臨床效果上并沒有明顯差異,但失敗方式有所不同;(3)目前,無菌性松動和對側(cè)間室病變的進(jìn)展仍是單髁假體失敗的主要方式;(4)采用生物固定和基于CT或MRI等影像資料的個性化假體設(shè)計可能是未來單髁假體的發(fā)展方向。
[Abstract]:Background: single condylar arthroplasty has been developing rapidly in recent years, and the operating volume has increased significantly in the world. But there is no systematic review of monomondylar prosthesis at present. Objective: to review the history and present situation of the evolution and development of single condylar prosthesis. To discuss the classification, characteristics and clinical effect of monomondylar prosthesis in common use so as to provide guidance for clinical practice. Methods: Pub Med and Wanfang database were searched for articles related to the clinical effects of monodondylar prosthesis and monodondylar prosthesis. A total of 177articles were retrieved, 35 articles were excluded from repetitive studies, and 4 annual reports of four major joint registration centers were added. A total of 39 articles were reviewed. Results and conclusions the monomondylar prosthesis has matured gradually after more than 60 years of tortuous development. The 10-year survival rate of the prosthesis reported in the literature has exceeded 90%. At present, the mainstream prostheses are mainly active platforms represented by Oxford 3 and fixed platforms represented by ZUK and Link. There is no significant difference in long-term clinical effects between the two types of prostheses. But the way of failure is different. Aseptic loosening and the progression of contralateral ventricular disease are still the main failure modes of monomondylar prostheses. (4) Bio-fixation and personalized prosthesis design based on CT or MRI image data may be the development direction of monomondylar prostheses in the future.
【作者單位】： 北京大學(xué)中日友好臨床醫(yī)學(xué)院;中日友好醫(yī)院;
【分類號】：R687.4

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