本文關(guān)鍵詞： 小劑量 醒腦靜注射液 中重型顱腦損傷 作用評(píng)價(jià)　出處：《重慶理工大學(xué)》2016年碩士論文　論文類型：學(xué)位論文

【摘要】：顱腦損傷(TBI)是平戰(zhàn)結(jié)合的一種常見病。在中國(guó),每年約有60萬人死亡,約有10萬人死亡,造成直接經(jīng)濟(jì)損失超過10億元人民幣。腦損傷的發(fā)生率最高,死亡率為第一,它已成為一個(gè)嚴(yán)重的社會(huì)危害。顱腦損傷的死亡率仍然很高,在神經(jīng)外科中對(duì)其治療方法的研究仍然是研究的重點(diǎn)。但很少有重視早期干預(yù)的大腦損傷。目的:通過對(duì)在中重型顱腦損傷患者治療中使用小劑量醒腦靜注射液后的效果進(jìn)行評(píng)價(jià),來尋求對(duì)該類型患者有效的治療方法,以減少費(fèi)用,改善預(yù)后,降低死亡率。方法:采用單盲隨機(jī)對(duì)照試驗(yàn)設(shè)計(jì)。通過對(duì)重慶市江津區(qū)中心醫(yī)院神經(jīng)外科從2012年5月至2014年4月收治的中重型顱腦損傷患者,共120例進(jìn)行研究。將患者隨機(jī)分為60例治療組和60例對(duì)照組。治療組在常規(guī)治療基礎(chǔ)上加用醒腦靜注射液10ml靜滴,每日一次;對(duì)照組給予常規(guī)治療。通過對(duì)患者GCS評(píng)分、手術(shù)患者顱內(nèi)壓測(cè)值、并發(fā)癥的發(fā)生(肺部感染、消化道出血、癲癇)進(jìn)行觀察、比較。本研究中各種計(jì)數(shù)資料采用X2檢驗(yàn),對(duì)計(jì)量資料采用t檢驗(yàn)。結(jié)果:治療組在提高GCS評(píng)分、降低顱內(nèi)壓、降低肺部感染發(fā)生率、消化道出血發(fā)生率等方面優(yōu)于對(duì)照組(P0.05)。在降低癲癇發(fā)生率方面,與對(duì)照組無顯著差異(P0.05)。結(jié)論:在中重型顱腦損傷患者的治療中,通過使用小劑量醒腦靜注射液(10ml),能夠達(dá)到提高GCS評(píng)分、降低顱內(nèi)壓、降低肺部感染和消化道出血發(fā)生率的作用。由此可降低治療費(fèi)用,改善預(yù)后,降低死亡率。
[Abstract]:Brain injury (TBI) is a common disease combined with peacetime and war. In China, about 600,000 people die each year and 100,000 die, causing direct economic losses of more than 1 billion yuan. The incidence of brain injury is the highest, and the death rate is the first. It has become a serious social hazard. The mortality rate of brain injury is still very high. The research on the treatment of neurosurgery is still the focus of the research. However, little attention has been paid to the early intervention of brain injury. Objective: to use small dose Xingnaojing injection in the treatment of patients with moderate and severe craniocerebral injury. After the evaluation of the effect, To find an effective treatment for this type of patient to reduce costs and improve prognosis. Methods: a single blind randomized controlled trial was used to treat the patients with moderate and severe craniocerebral injury in the neurosurgery department of the Central Hospital of Jiang Jin District of Chongqing from May 2012 to April 2014. 120 patients were randomly divided into treatment group (n = 60) and control group (n = 60). The treatment group received 10 ml Xingnaojing injection once a day on the basis of routine treatment, and the control group was given routine treatment. Intracranial pressure (ICP), complications (pulmonary infection, gastrointestinal hemorrhage, epilepsy) were observed and compared. Results: the treatment group was superior to the control group in improving GCS score, reducing intracranial pressure, reducing the incidence of pulmonary infection, and the incidence of gastrointestinal hemorrhage. Conclusion: in the treatment of patients with moderate and severe craniocerebral injury, low dose Xingnaojing injection 10 ml can improve GCS score and reduce intracranial pressure. The effect of reducing the incidence of pulmonary infection and gastrointestinal hemorrhage can reduce the cost of treatment, improve prognosis and reduce mortality.
【學(xué)位授予單位】：重慶理工大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R651.15

【引證文獻(xiàn)】

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1 段澤武;靳小磊;;針刺康復(fù)訓(xùn)練聯(lián)合中藥醒腦靜注射液對(duì)重型顱腦損傷患者功能恢復(fù)的影響分析[J];中西醫(yī)結(jié)合心血管病電子雜志;2017年22期

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