發(fā)布時間：2018-04-28 22:38

  本文選題：淀粉 + 羥乙基纖維素�。� 參考：《生物醫(yī)學工程研究》2017年04期

【摘要】：本研究采用低溫等離子體技術(shù)和冷凍干燥工藝制備了半互穿網(wǎng)絡(luò)淀粉基止血海綿。通過測試止血海綿的吸水率和膨脹率優(yōu)化了實驗方案及制備工藝,掃面電鏡照片顯示,本研究制備的海綿具有均勻相互貫通的網(wǎng)絡(luò)骨架多孔結(jié)構(gòu)。兔肝腎止血實驗表明該止血海綿止血快,出血量少,具有良好的止血效果。大鼠體內(nèi)降解實驗表明,淀粉止血海綿4周后可被降解吸收。本研究制備的半互穿網(wǎng)絡(luò)淀粉基止血海綿,是一種快速有效的可吸收的止血敷料,在外科手術(shù)中具有很好的應(yīng)用前景。
[Abstract]:In this study, semi-interpenetrating network starch-based hemostatic sponge was prepared by low temperature plasma technology and freeze-drying process. By testing the water absorption and expansion rate of hemostatic sponge, the experimental scheme and preparation process were optimized. The SEM photos showed that the sponge prepared in this study had a porous network structure with uniform interpenetrating network. The hemostatic experiment of rabbit liver and kidney showed that the hemostatic sponge had good hemostatic effect. In vivo degradation experiments in rats showed that starch hemostatic sponge could be degraded and absorbed after 4 weeks. The semi-interpenetrating network starch-based hemostatic sponge is a fast and effective absorbable hemostatic dressing and has a good prospect of application in surgery.
【作者單位】： 山東省藥學科學院山東省醫(yī)用高分子材料重點實驗室;山東省中醫(yī)院;
【基金】：山東省糖產(chǎn)業(yè)省級重點實驗室聯(lián)盟資助項目(山東省科技廳2015年2060599科目)
【分類號】：R318.08
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本文編號：1817222