本文選題：機械性取栓 + 生物力學��； 參考：《中國生物醫(yī)學工程學報》2014年01期

【摘要】：本研究模擬了兩款鎳鈦三維螺旋狀機械性取栓器(MERD)在徑向壓握、徑向釋放和血管內(nèi)遷移過程中的情況,并對單個模型結構在各個接觸載荷下的力學性能進行分析。建立了兩款機械性取栓器、壓握工具以及目標血管的有限元模型。對圓柱狀壓握工具施加向內(nèi)的徑向位移UR=+0.9 mm,壓握取栓器至外徑為2.9 mm;將壓握工具恢復到原始尺寸,建立血管/取栓器接觸關系;牽引取栓器近頭端,使其在血管壁內(nèi)遷移滑動。分析和比較兩款取栓器在壓握狀態(tài)下的徑向支撐力(RF)和最大主應變(MPS)峰值,釋放狀態(tài)下變形血管的等效應力峰值(VMS),遷移過程中取栓器的最大主應變、血管壁的等效應力峰值以及分析末期取栓器形態(tài)。結果表明,Ⅰ型和Ⅱ型取栓器的最大壓握主應變峰值分別為3.23%和3.61%,Ⅰ型取栓器壓握過程更加安全;當壓握外徑為3.0 mm時,Ⅰ型取栓器的徑向支撐力為1.96 N,較Ⅱ型取栓器小21.6%,更容易壓握;Ⅰ型結構在釋放和遷移的過程中,造成血管壁應力集中的峰值分別為0.378 MPa和0.509 MPa,較Ⅱ型結構大21.6%和30.5%。本研究結果可以用于螺旋狀機械性取栓器的結構優(yōu)化設計,提高其生物力學性能,在工程和臨床上具有重要應用價值。
[Abstract]:In this study, two three dimensional helical nickel titanium bolt removers, MERD), were simulated during radial pressure grip, radial release and intravascular migration, and the mechanical properties of individual model structures under various contact loads were analyzed.Two finite element models of mechanical thrombolizer, gripper and target vessel were established.Apply an inward radial displacement of 0.9 mm to the cylindrical press grip tool, and 2.9 mm diameter to the external diameter of the pressure holder; restore the pressure grip tool to its original size and establish a vascular / latch contact relationship; pull the latch closer to the end of the head,Make it move and slide in the wall of the blood vessel.The peak values of radial support force (RFF) and maximum principal strain (MPS) of the two kinds of bolting devices under the pressure grip state were analyzed and compared. The peak equivalent stress of the deformed blood vessels in the release state was analyzed and compared. The maximum principal strain of the bolt extractor during the migration process was also analyzed and compared.The peak equivalent stress of the vessel wall and the morphology of the end-stage thrombectomy were analyzed.The results showed that the maximum principal strain of type 鈪，

本文編號：1771252