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邊界振動(dòng)流場對單個(gè)紅細(xì)胞損傷影響分析

發(fā)布時(shí)間:2018-03-20 07:08

  本文選題:邊界振動(dòng)流場 切入點(diǎn):紅細(xì)胞 出處:《生物醫(yī)學(xué)工程學(xué)雜志》2016年01期  論文類型:期刊論文


【摘要】:現(xiàn)有的外磁驅(qū)動(dòng)植入式軸流血泵,由于植入環(huán)境、受驅(qū)動(dòng)力不均勻等因素會產(chǎn)生振動(dòng)。本文通過對單個(gè)紅細(xì)胞進(jìn)行建模,仿真分析單個(gè)紅細(xì)胞在邊界振動(dòng)流場中的變形與受力,并與紅細(xì)胞在血泵中遭受機(jī)械損傷的機(jī)制相結(jié)合,研究邊界振動(dòng)流場對紅細(xì)胞損傷的影響。研究結(jié)果表明,在邊界振動(dòng)流場中紅細(xì)胞的形狀變化情況、受力狀況和周圍速度場等因素均會導(dǎo)致紅細(xì)胞損傷。通過對上述內(nèi)容的研究,本文期待可為改善血泵的溶血現(xiàn)象提供理論依據(jù)。
[Abstract]:The existing external magnetic drive implantable axial bleeding pump will vibrate due to the non-uniform driving force and other factors. In this paper, the deformation and force of single red blood cell in the boundary vibration flow field are simulated and analyzed by modeling the single red blood cell. The effect of boundary vibration flow field on erythrocyte damage was studied by combining with the mechanism of erythrocyte mechanical injury in blood pump. The results show that the shape of red blood cell changes in the boundary vibration flow field. The stress condition and the surrounding velocity field will cause erythrocyte damage. Through the study of the above contents, we hope to provide a theoretical basis for improving the hemolysis phenomenon of the blood pump.
【作者單位】: 中南大學(xué)機(jī)電工程學(xué)院;
【基金】:國家自然科學(xué)基金資助項(xiàng)目(31271057;51475477)
【分類號】:R318.01
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本文編號:1638013

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