本文關(guān)鍵詞：摻鉀納米羥基磷灰石對(duì)牙本質(zhì)小管及其表面硬度、粗糙度影響的研究　出處：《福建醫(yī)科大學(xué)》2013年碩士論文　論文類(lèi)型：學(xué)位論文

  更多相關(guān)文章： 羥基磷灰石 掃描電鏡 硬度 粗糙度

【摘要】：研究目的 進(jìn)行固定冠橋修復(fù)時(shí)，，為了滿足修復(fù)體所需要的足夠空間，臨床上往往需要磨除大量牙體組織，導(dǎo)致牙本質(zhì)敏感。牙本質(zhì)敏感的發(fā)病機(jī)制目前有三種假說(shuō)，其中流體動(dòng)力學(xué)理論被廣泛接受，該理論認(rèn)為，作用于牙本質(zhì)外部的刺激引起了牙本質(zhì)小管內(nèi)容物向內(nèi)或向外的異常流動(dòng)，這種液體流動(dòng)刺激到牙髓，引起牙髓神經(jīng)的興奮，產(chǎn)生痛覺(jué)。目前，臨床上所使用的脫敏劑基本上都是基于這個(gè)理論研制而成。納米羥基磷灰石及其復(fù)合物在口腔治療及保健領(lǐng)域的應(yīng)用越來(lái)越多的受到國(guó)內(nèi)外學(xué)者的關(guān)注，有研究表明納米羥基磷灰石能有效封閉牙本質(zhì)小管，本實(shí)驗(yàn)用摻鉀納米羥基磷灰石處理牙本質(zhì)表面，掃描電鏡下觀察這種新型材料封閉離體牙本質(zhì)小管的情況，測(cè)量其對(duì)牙本質(zhì)表面硬度及粗糙度是否產(chǎn)生影響，以期為新型牙脫敏材料的研制提供理論依據(jù)。 實(shí)驗(yàn)方法 收集因正畸拔除、完整無(wú)齲壞的上頜第一前磨牙，制備牙本質(zhì)薄片，分別用Gluma脫敏劑、納米羥基磷灰石、摻鉀納米羥基磷灰石處理牙本質(zhì)表面，掃描電鏡下觀察其封閉牙本質(zhì)小管的情況，用顯微硬度計(jì)和粗糙度測(cè)量?jī)x分別測(cè)量牙本質(zhì)表面硬度值以及粗糙度值的改變情況，將所得到的結(jié)果用SPSS13.0軟件進(jìn)行統(tǒng)計(jì)學(xué)分析。 實(shí)驗(yàn)結(jié)果 1、掃描電鏡下，三種不同處理材料均能有效封閉牙本質(zhì)小管口，摻鉀納米羥基磷灰石能夠深入到牙本質(zhì)小管內(nèi)部約16μm、納米羥基磷灰石能夠深入到牙本質(zhì)小管內(nèi)部約12μm。 2、經(jīng)摻鉀納米羥基磷灰石處理過(guò)的牙本質(zhì)表面，硬度平均值約為58.2733HV，硬度值高于未做任何處理的牙本質(zhì)樣本。 3、經(jīng)摻鉀納米羥基磷灰石處理過(guò)的牙本質(zhì)表面，掃描電鏡下可見(jiàn)牙本質(zhì)小管口幾乎全部被封閉，牙本質(zhì)表面平整度不一，有斑塊狀突起，粗糙度平均值為3.7851μm，高于未做任何處理的牙本質(zhì)樣本。 結(jié)論 1、摻鉀納米羥基磷灰石能有效封閉牙本質(zhì)小管，并深入到牙本質(zhì)小管內(nèi)部約16μm。 2、摻鉀納米羥基磷灰石提高牙本質(zhì)表面維氏硬度值。 3、摻鉀納米羥基磷灰石使牙本質(zhì)表面粗糙度Ra值增大。
[Abstract]:Research purpose In order to meet the need of enough space for the restoration of fixed crown and bridge, there are three hypotheses about the pathogenesis of dentin sensitivity, which usually needs to remove a large number of dentin tissues in clinic. Among them, the theory of hydrodynamics is widely accepted, which holds that the stimulation acting on the external dentin causes abnormal flow of the contents of the dentine tubules, which stimulates the dental pulp. Causes the pulp nerve to excite, produces the pain sensation. At present. The desensitizer used in clinic is based on this theory. The application of nano-hydroxyapatite and its complex in the field of oral treatment and health care has attracted more and more attention of scholars at home and abroad. Some studies have shown that nano-hydroxyapatite can effectively seal the dentine tubules. In this experiment, potassium doped nano-hydroxyapatite was used to treat the dentin surface. Scanning electron microscope was used to observe the effect of this new material on the isolated dentine tubules. In order to provide a theoretical basis for the development of new desensitization materials, the influence on the hardness and roughness of dentin surface was measured. Experimental method The maxillary first premolars without caries were extracted by orthodontics and the dentin slices were prepared. The dentin surface was treated with Gluma desensitizer nano-hydroxyapatite and potassium doped nano-hydroxyapatite respectively. The microhardness and roughness of the dentine surface were measured by microhardness meter and roughness tester respectively. The results were analyzed by SPSS13.0 software. Experimental results 1. Under scanning electron microscope, the dentine tubules could be effectively sealed by three different materials, and potassium doped nano-hydroxyapatite could penetrate into the dentin tubules about 16 渭 m. Nano hydroxyapatite can penetrate into the dentin tubules about 12 渭 m. 2, the average hardness of the dentine treated with potassium doped nano-hydroxyapatite is about 58.2733 HVV, which is higher than that of the untreated dentin sample. 3. On the surface of dentin treated with potassium doped nano-hydroxyapatite, almost all dentine tubules were closed under scanning electron microscope. The mean roughness was 3.7851 渭 m, which was higher than that of untreated dentin samples. Conclusion 1. Potassium doped nano-hydroxyapatite can effectively seal the dentine tubules and penetrate into the dentin tubules about 16 渭 m. 2. Potassium-doped nano hydroxyapatite increased Vickers hardness of dentin surface. 3. K-doped nano hydroxyapatite increases the roughness Ra value of dentin surface.
【學(xué)位授予單位】：福建醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2013
【分類(lèi)號(hào)】：R783.1

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