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面神經F波用于評估中國聽神經瘤患者術前術中術后面神經功能的研究

發(fā)布時間:2021-05-27 10:17
  目的:本對119例經顯微手術治療的聽神經瘤(VS)患者進行回顧性分析及術后隨訪,評估面神經F波各項電生理參數與面神經功能障礙的關系,同時一并分析面神經功能與腫瘤大小,內聽道直徑(IAM),術后局部出血以及術前、術中、術后面神經F波參數的關系。方法資料:對中南大學湘雅醫(yī)院顱底外科中心自2011年7月至2012年10月間由袁賢瑞教授主刀的119例聽神經瘤病例進行回顧分析,所有病例均經枕下乙狀竇后內聽道入路切除腫瘤。所有患者術前均完善顱底HRCT及顱腦平掃增強MRI檢查,并在術前,術中及術后進行面神經F波電生理評測。術中詳細記錄了聽神經瘤的大小和類型以及腫瘤與面神經的關系。多數患者接受手術治療后存在面神經功能障礙。以House-Brackmann (HB)面神經功能分級作為面神經功能評價指標。對所有病例術后過15天,3個月,6個月,9個月和1年的時段定期進行隨訪,觀察腫瘤是否復發(fā),術后面神經癱瘓程度及面部F波的評估。結果119例患者中,1例屬于復發(fā)再次手術病例,術前HB分級為Ⅳ級。而且該患者術前、術中F波檢測沒有波形,因此排除,118例納入統計分析。在這118例患者中,2(1.69%)例屬于... 

【文章來源】:中南大學湖南省 211工程院校 985工程院校 教育部直屬院校

【文章頁數】:88 頁

【學位級別】:碩士

【文章目錄】:
摘要
ABSTRACT
Table of Abbreviations
Preface
    Overview
    Operative technique
    Significance of research
    Facial F-wave Monitoring
Ⅰ.Clinical Materials and Methods.第一章 資料與方法
    1.1. Overview
    1.2. Clinical Manifestation of VS
    1.3. Pre-operative Investigations
    1.4. Facial F-wave recording
    1.5. Facial F-waves parameters
    1.6. Surgical technique
    1.7. Patients grouping and post-operative outcomes
    1.8. Statistical analysis
Ⅱ Results
    2.1. Patients' data
    2.2. Size of VS& IAM
    2.3. Preoperative HB Score and Facial F-wave parameters
    2.4. Postoperative HB Score and Facial F-wave parameters
    2.5. Intraoperative Facial F-wave parameters
    2.6. Follow-up HB Scores & VS recurrence
    2.7. Correlation between parameters of Facial F-wave and dimension of VS,IAM & postoperative hemorrhage
    2.8. Correlation regarding Pre-operative HB score
    2.9. Correlation regarding Post-operative HB score
    2.10. Correlation rega rding follow-up HB scores
Ⅲ.Discussion
    3.1. Overview
    3.2. Sensitivity of different F-wave parameters
    3.3. Pre-operative HB score and its correlation with IAM & size ofVS
    3.4. Pre-operative HB score and its correlation with F-waveparameters
    3.5. Post-operative HB score and its correlation with F-waveparameters
    3.6. Post-operative HB score and its correlation with post-operativehemorrhage
    3.7. Follow-up HB scores and its correlation with F-waveparameters
Ⅳ. Conclusion
Ⅴ. Prospective
Ⅵ. References
Review
    Overview
    Intra-operative Facial nerve monitoring
    EMG monitoring
    F wave monitoring
    Characteristics of CN Ⅶ Dysfunction in VS
    Sensitivity of F-wave parameters
    Conclusion
    References
Chinese summary 中文介紹
Acknowledgement
Personal Identity



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