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補體系統(tǒng)與急性缺血性腦血管病的關(guān)系研究進展

發(fā)布時間:2019-02-09 13:07
【摘要】:正急性缺血性卒中是臨床上常見的腦血管疾病,其病因及發(fā)病機制復(fù)雜。補體系統(tǒng)是人類體液固有免疫系統(tǒng)的重要組成部分,在抵抗微生物入侵及維持機體內(nèi)環(huán)境穩(wěn)態(tài)中發(fā)揮重要作用。近年來,補體系統(tǒng)在急性缺血性腦血管病中的作用逐漸被重視。激活補體系統(tǒng)的有效途徑有3條:經(jīng)典途徑、凝集素途徑和旁路途徑[1],另外還可能存在外源性補體激活途徑[2]。這些激活補體
[Abstract]:Acute ischemic stroke is a common cerebrovascular disease, its etiology and pathogenesis are complicated. Complement system is an important part of the innate immune system of human body fluid, which plays an important role in resisting microbial invasion and maintaining the homeostasis of the environment. In recent years, the role of complement system in acute ischemic cerebrovascular disease has been paid more and more attention. There are three effective ways to activate complement system: classical pathway, lectin pathway and bypass pathway [1]. In addition, there may be exogenous complement activation pathway [2]. These activated complements
【作者單位】: 中國醫(yī)科大學(xué)附屬盛京醫(yī)院神經(jīng)內(nèi)科;
【基金】:遼寧省科學(xué)技術(shù)規(guī)劃(2012225069) 沈陽市科學(xué)技術(shù)計劃(F12-277-1-02)
【分類號】:R743.3
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本文編號:2418993

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