顱內(nèi)外大動(dòng)脈狹窄與進(jìn)展性卒中的相關(guān)性
發(fā)布時(shí)間:2018-11-10 20:24
【摘要】:研究目的 研究顱內(nèi)外大動(dòng)脈狹窄與進(jìn)展性卒中(stroke in progression, SIP)的相關(guān)性,進(jìn)一步探討進(jìn)展性卒中的相關(guān)危險(xiǎn)因素。 研究方法 選取2012年2月~2012年12月在北京軍區(qū)總醫(yī)院神經(jīng)內(nèi)科住院經(jīng)頭顱核磁證實(shí)的急性缺血性腦卒中患者120例,按照發(fā)病72小時(shí)內(nèi)病情是否加重(NIHSS評(píng)分≥4)分成進(jìn)展組60例和對(duì)照組60例,兩組患者入院后顱內(nèi)血管評(píng)估使用頭頸動(dòng)脈CTA/MRA,其中CTA52例,MRA68例;顱外血管采用頸動(dòng)脈超聲進(jìn)行評(píng)估,比較兩組患者顱內(nèi)外大動(dòng)脈狹窄程度及與進(jìn)展性卒中的相關(guān)性。 結(jié)果 在進(jìn)展組內(nèi)顱內(nèi)外大動(dòng)脈狹窄的發(fā)生率明顯高于對(duì)照組。進(jìn)展組MCA狹窄14例,頸內(nèi)動(dòng)脈狹窄10例;對(duì)照組MCA狹窄9例,頸內(nèi)動(dòng)脈狹窄8例。多因素Logistic回歸分析顯示,合并有高血壓、高脂血癥、高同型半胱胺酸血癥、頸動(dòng)脈斑塊及大腦中動(dòng)脈狹窄是進(jìn)展性卒中發(fā)生的獨(dú)立危險(xiǎn)因素(OR=3.32,95%CI:1.01-5.03; OR=2.74,95%CI:1.07-4.53;OR=2.48,95%CI:1.09-4.45; OR=5.75,95%CI:1.19-6.65; OR=2.59,95%CI:1.04-4.34)。 結(jié)論 顱內(nèi)外大動(dòng)脈狹窄程度與進(jìn)展性卒中的發(fā)生呈正相關(guān),通過積極評(píng)估血管采取及時(shí)干預(yù)可延緩卒中的進(jìn)展。
[Abstract]:Objective to study the correlation between intracranial and extracranial artery stenosis and progressive stroke (stroke in progression, SIP) and to explore the risk factors of progressive stroke. Methods from February 2012 to December 2012, 120 patients with acute ischemic stroke who were admitted to the Department of Neurology, Beijing military region General Hospital from February 2012 to December 2012 were selected. According to the severity of the disease within 72 hours (NIHSS score 鈮,
本文編號(hào):2323526
[Abstract]:Objective to study the correlation between intracranial and extracranial artery stenosis and progressive stroke (stroke in progression, SIP) and to explore the risk factors of progressive stroke. Methods from February 2012 to December 2012, 120 patients with acute ischemic stroke who were admitted to the Department of Neurology, Beijing military region General Hospital from February 2012 to December 2012 were selected. According to the severity of the disease within 72 hours (NIHSS score 鈮,
本文編號(hào):2323526
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