本文選題：彌散張量成像 + 多模態(tài)影像　； 參考：《蚌埠醫(yī)學院》2017年碩士論文

【摘要】：目的:應用功能神經導航實現(xiàn)T1WI、DTI、DTT等多種模態(tài)的融合,用以指導涉及主要功能纖維束的顱內病變手術,以期達到最小化的神經功能損傷以及最大化病灶切除的效果。方法:觀察2013年12月-2016年8月,我院神經外科25例腦功能區(qū)腫瘤在多模態(tài)神經導航輔助下的手術情況,隨機抽取同期在傳統(tǒng)神經導航輔助下手術切除的25例病例作為對照組。比較并分析兩組手術在腫瘤全切率、術后致殘率、平均住院時間、預后等方面的差異性。結果:研究組平均手術時間5.6±1.3 h,對照組平均5.4±1.5 h,差異無統(tǒng)計學意義(P0.05)。研究組平均住院時間16.35±4.29 d,對照組19.57±6.15 d,研究組平均住院時間明顯短于對照組(P0.05)。研究組全切除19例(76%),次全切除4例,部分切除2例;對照組全切除12例(48%),次全切除9例,部分切除4例;研究組腫瘤全切除率高于對照組(P0.05)。研究組出現(xiàn)并發(fā)癥4例(16%),對照組13例(52%),兩組差異顯著。研究組平均KPS評分為89.12±17.35分,對照組為73.56±18.21分,差異有統(tǒng)計學意義(p0.05)。結論:融合DTT等多種模態(tài)的功能神經導航,可以顯著提高鄰近錐體束及視放射等功能纖維束腦腫瘤的全切除率,有效降低患者術后致殘率,臨床療效顯著。
[Abstract]:Objective: to use functional neuronavigation to realize the fusion of T1WIN DTI DTT and other modes to guide the operation of intracranial lesions involving the main functional fibrous bundles in order to minimize the injury of nerve function and maximize the effect of lesion resection. Methods: from December 2013 to August 2016, 25 patients with brain functional area tumors in our hospital were treated with multimodal neuronavigation and 25 patients were randomly selected as control group. The difference of total tumor resection rate, postoperative disability rate, average hospitalization time and prognosis between the two groups were compared and analyzed. Results: the mean operative time was 5.6 鹵1.3 hours in the study group and 5.4 鹵1.5 hours in the control group. There was no significant difference between the two groups (P 0.05). The average hospitalization time was 16.35 鹵4.29 days in the study group and 19.57 鹵6.15 days in the control group. The average hospitalization time in the study group was significantly shorter than that in the control group (P 0.05). There were 19 cases of total resection, 4 cases of subtotal resection, 2 cases of partial resection in the study group, 12 cases of total resection, 9 cases of subtotal resection and 4 cases of partial resection in the control group. The total resection rate of tumor in the study group was higher than that in the control group (P 0.05). Complications were found in 4 cases in the study group and in 13 cases in the control group. The average KPS score was 89.12 鹵17.35 in the study group and 73.56 鹵18.21 in the control group. The difference was statistically significant (P 0.05). Conclusion: the fusion of DTT and other modes of functional neuronavigation can significantly improve the rate of total resection of brain tumors of the adjacent pyramidal tract and visual radiation, and effectively reduce the rate of postoperative disability, and the clinical efficacy is remarkable.
【學位授予單位】：蚌埠醫(yī)學院
【學位級別】：碩士
【學位授予年份】：2017
【分類號】：R739.4

【參考文獻】

相關期刊論文 前10條

1 郭致飛;趙兵;吳德俊;李德坤;江濤;王少華;仰鵬志;孫錦章;沈杰;;大腦中動脈瘤破裂合并顱內血腫的早期顯微手術治療[J];安徽醫(yī)藥;2016年08期

2 甄雪克;張黎;于炎冰;;面肌痙攣顯微血管減壓術后聽力障礙的預后及影響因素分析[J];中華神經外科雜志;2016年08期

3 余龍洋;李亞楠;陳玉坤;汪劍;岳志健;;神經導航融合DTI在大腦功能區(qū)附近病變手術的臨床應用[J];中國微侵襲神經外科雜志;2015年10期

4 張翔圣;張鑫;張慶榮;吳琪;文立利;茅磊;吳偉;杭春華;;三維DSA與MRI或CT融合技術在顱內動靜脈畸形治療中的應用價值[J];中國腦血管病雜志;2015年09期

5 劉通;劉輝;張建寧;朱濤;;顯微外科手術切除脊髓髓內腫瘤的療效[J];中華神經外科雜志;2015年06期

6 孫國臣;朱明啟;陳曉雷;侯遠征;余新光;李安民;朱儒遠;李鋼;周定標;許百男;;術中高場強MRI引導下成人幕上膠質瘤切除程度的定量研究[J];中國微侵襲神經外科雜志;2015年05期

7 白少聰;陳曉雷;耿杰峰;吳東東;余新光;許百男;;高場強術中磁共振成像及神經導航在累及視放射的顳葉膠質瘤手術中的應用[J];中華外科雜志;2015年05期

8 李群喜;趙曉晶;朱軍;付愛軍;張云鶴;邵宏超;張軍偉;劉剛;;體感誘發(fā)電位、運動誘發(fā)電位聯(lián)合監(jiān)測在脊髓髓內腫瘤切除術中的應用[J];山東醫(yī)藥;2014年44期

9 黃錦峰;喻軍華;王璨;陳志勇;袁學剛;劉斌;吳新宇;胡太可;;術中超聲在顱腦深部病灶顯微切除術中的應用[J];中國微侵襲神經外科雜志;2014年11期

10 崔志強;凌至培;潘隆盛;陳立鋒;徐欣;齊葉青;陳曉雷;張遠征;許百男;;術中磁共振聯(lián)合顯微鏡下導航在難治性癲腦深部小病變切除術中的應用[J];中國微侵襲神經外科雜志;2014年09期

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