本文選題：可降解鎂合金覆膜支架　切入點：Willis覆膜支架　出處：《介入放射學(xué)雜志》2016年02期

【摘要】：目的評價可降解鎂合金覆膜支架治療兔頸總動脈側(cè)壁型動脈瘤的可行性。方法 20只新西蘭大白兔飼養(yǎng)1周后采用間斷式外翻縫合法將右側(cè)頸總動脈與靜脈囊吻合,構(gòu)建20枚頸總動脈側(cè)壁型動脈瘤。72 h內(nèi)分別實施可降解鎂合金覆膜支架植入術(shù)和Willis覆膜支架植入術(shù)。術(shù)前、術(shù)后即刻、術(shù)后3、6、12個月作DSA造影檢查,對比動脈瘤閉塞、內(nèi)漏、血管痙攣、血管損傷、血栓事件、血管閉塞和狹窄等情況。結(jié)果可降解鎂合金覆膜支架和Willis覆膜支架各植入10枚,技術(shù)成功率為100%。支架植入術(shù)后即刻造影顯示所有動脈瘤腔完全閉塞,載瘤動脈通暢,可降解鎂合金覆膜支架組血管痙攣3例,Willis覆膜支架組血管痙攣1例;術(shù)后3、6、12個月復(fù)查造影顯示動脈瘤完全消失,載瘤動脈通暢。結(jié)論可降解鎂合金覆膜支架治療兔頸總動脈側(cè)壁型動脈瘤是可行的。
[Abstract]:Objective to evaluate the feasibility of degradable magnesium alloy coated stent in the treatment of lateral wall aneurysms of common carotid artery in rabbits. Methods Twenty New Zealand white rabbits were raised for 1 week to anastomose the right common carotid artery with the venous sac by intermittent valgus suture. Twenty common carotid artery lateral wall aneurysms were implanted with degradable magnesium alloy stent and Willis stent respectively within 72 hours. DSA angiography was performed immediately before, immediately after operation, and 12 months after operation, and compared with occlusion and internal leakage of aneurysm. Vasospasm, vascular injury, thrombotic events, vascular occlusion and stenosis. Results 10 biodegradable magnesium alloy coated stents and 10 Willis coated stents were implanted. The technical success rate was 100%. Immediately after stent implantation, all aneurysms were completely occluded, aneurysm carrying arteries were unobstructed, and 3 cases of vasospasm were found in the degradable magnesium alloy coated stent group, 1 case in the Willis covered stent group. The results showed that the aneurysm disappeared completely and the aneurysm was unobstructed. Conclusion it is feasible to treat the lateral wall aneurysm of the common carotid artery with degradable magnesium alloy stent.
【作者單位】： 蘇州大學(xué)醫(yī)學(xué)部;上海交通大學(xué)附屬第六人民醫(yī)院介入影像科;
【基金】：國家自然科學(xué)基金(81201199)
【分類號】：R743
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本文編號：1677112