本文選題：膠質(zhì)瘤　切入點(diǎn)：手術(shù)切除程度　出處：《皖南醫(yī)學(xué)院》2017年碩士論文　論文類型：學(xué)位論文

【摘要】：目的:回顧分析影響膠質(zhì)瘤患者生存期的相關(guān)因素,總結(jié)膠質(zhì)瘤臨床治療經(jīng)驗(yàn)。方法:收集2013年1月~2015年9月皖南醫(yī)學(xué)院第一附屬醫(yī)院138例膠質(zhì)瘤患者的臨床資料,對(duì)患者的臨床資料、手術(shù)切除程度、術(shù)后并發(fā)癥、腫瘤病理結(jié)果、術(shù)后是否放化療、生存期等進(jìn)行整理,對(duì)影響膠質(zhì)瘤患者生存期相關(guān)因素進(jìn)行統(tǒng)計(jì)學(xué)分析。結(jié)果:單因素分析患者生存期影響因素:年齡≤50歲膠質(zhì)瘤患者生存期較年齡50歲患者明顯延長(zhǎng)(p=0.0057);病理低級(jí)別組的中位生存期明顯長(zhǎng)于高級(jí)別組的生存期(p0.0001);術(shù)前KPS評(píng)分≥70患者的生存期較術(shù)前KPS評(píng)分70患者的生存期延長(zhǎng)(p=0.0003);手術(shù)全切組患者的生存期明顯長(zhǎng)于次全切組(p=0.0016);術(shù)后放化療患者的生存期明顯優(yōu)于未行放化療患者(p0.0001)。應(yīng)用COX多因素分析顯示腫瘤切除程度(p0.0001)、術(shù)后是否放化療(p=0.003)、術(shù)前KPS評(píng)分(p=0.003)、腫瘤病理級(jí)別(p0.0001)4個(gè)因素與膠質(zhì)瘤患者生存期明顯相關(guān)。結(jié)論:低級(jí)別膠質(zhì)瘤、術(shù)前KPS評(píng)分≥70的患者預(yù)后較好;手術(shù)切除程度越高、術(shù)后輔助放化療可明顯延長(zhǎng)患者生存期。
[Abstract]:Objective: to retrospectively analyze the related factors affecting the survival time of glioma patients, and summarize the clinical experience of glioma treatment. Methods: from January 2013 to September 2015, the clinical data of 138 glioma patients in the first affiliated Hospital of Wannan Medical College were collected. The clinical data, surgical resection degree, postoperative complications, tumor pathological results, postoperative radiotherapy and chemotherapy, survival time, etc. Results: univariate analysis showed that the survival time of patients with glioma 鈮，

本文編號(hào)：1642219