本文選題：神經(jīng)梅毒 + 腦脊液�。� 參考：《中國(guó)老年保健醫(yī)學(xué)》2015年05期

【摘要】：目的探討神經(jīng)梅毒的臨床表現(xiàn)、實(shí)驗(yàn)室檢查和影像學(xué)檢查特征。方法回顧性分析18例神經(jīng)梅毒患者的臨床表現(xiàn)、實(shí)驗(yàn)室檢查和影像學(xué)檢查資料。結(jié)果 18例神經(jīng)梅毒患者平均發(fā)病年齡53.83歲,其中主質(zhì)型8例(44.44%),其中麻痹性癡呆4例,脊髓癆3例,混合型1例;腦膜血管梅毒4例(22.22%);無(wú)癥狀型3例(16.67%);樹(shù)膠樣腫型2例(11.11%);腦膜炎型1例(5.56%)。血清血漿快速反應(yīng)素試驗(yàn)(RPR)、梅毒螺旋體顆粒凝集試驗(yàn)(TPPA)檢測(cè)均為陽(yáng)性。腦脊液檢查:18例患者TPPA均陽(yáng)性,9例RPR陽(yáng)性,9例腦脊液白細(xì)胞數(shù)≥10×106/L,7例腦脊液蛋白0.50g/L。影像學(xué)表現(xiàn)為:腦梗死,腦萎縮,腦白質(zhì)變性,額葉、顳葉、海馬區(qū)異常信號(hào)及大腦后動(dòng)脈閉塞,顱內(nèi)動(dòng)脈硬化。結(jié)論神經(jīng)梅毒表現(xiàn)多樣,臨床體征、血清學(xué)、腦脊液及影像學(xué)對(duì)于診斷神經(jīng)梅毒及分型有重要指導(dǎo)意義。
[Abstract]:Objective to investigate the clinical manifestations, laboratory and imaging features of neurosyphilis. Methods 18 cases of neurosyphilis were analyzed retrospectively. Results the average age of 18 patients with neurosyphilis was 53.83 years old. Among them, 8 cases had primary type of neurosyphilis (4 cases of paralytic dementia, 3 cases of tuberculosis and 1 case of mixed type). Meningeal vascular syphilis (n = 4), asymptomatic type (n = 3, n = 16), gum type (n = 2, n = 11) and meningitis type (n = 1, n = 5.56). Serum rapid response hormone test (RPRP) and Treponema pallidum agglutination test (TPPA) were all positive. Cerebrospinal fluid (CSF) examination showed TPPA positive in 9 cases and RPR positive in 9 cases. WBC count in cerebrospinal fluid was 鈮，

本文編號(hào)：2038476