中性粒細胞與淋巴細胞比值及紅細胞分布寬度對亞甲炎的診斷價值研究
[Abstract]:Objective to investigate the diagnostic value of neutrophil / lymphocyte ratio (NLR) and erythrocyte distribution width (RDW) in subthyroiditis. Methods from April 2014 to October 2016, 89 patients with subthyroiditis admitted in the second affiliated Hospital of Henan University of traditional Chinese Medicine were selected as the study group, 78 patients with other thyroid diseases and 80 healthy controls were selected. (NLR), thyroglobulin (Tg), thyroid binding globulin antibody (TG-Ab) and thyroid peroxidase antibody (TPOAb), were compared in each group by comparing the red blood cell distribution width (RDW), neutrophil / lymphocyte ratio (NLR), thyroglobulin (Tg), thyroid binding globulin antibody (TG-Ab) and thyroid peroxidase antibody (TPOAb), The difference of (TMAb) and FT3,FT4,TSH between (TRAb), thyroid microsomal antibody and FT3,FT4,TSH was studied. The relationship between RDW,NLR and other indexes was analyzed by Pearson correlation analysis and multiple stepwise linear regression analysis. ROC curve was used to compare the diagnostic value of each index. Results the RDW value of subthyroitis group and other groups were higher than that of normal control group, but the NLR value was lower than that of normal control group, RDW and TSH,TPOAb had correlation coefficient of -0.43 and 0.33 (P0.05). There was a positive correlation between NLR and FT3, the correlation coefficient was 0.47 (P0.05); ROC analysis curve showed that Tg is the best diagnostic index of subthyroiditis, RDW,NLR can also be used as a better diagnostic index. Conclusion NLR,RDW combined with Tg, is more effective in the diagnosis of thyroiditis.
【作者單位】: 河南中醫(yī)藥大學(xué)第二附屬醫(yī)院檢驗科;
【基金】:河南省科技攻關(guān)項目(132102310244)
【分類號】:R446.1;R581.4
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