發(fā)布時(shí)間：2018-03-18 18:08

  本文選題：糖尿病　切入點(diǎn)：iMSDE　出處：《實(shí)用醫(yī)學(xué)雜志》2017年12期 　論文類型：期刊論文

【摘要】：目的:評(píng)價(jià)基于非對(duì)比增強(qiáng)磁共振血管成像(NCE-MRA)技術(shù)的優(yōu)化運(yùn)動(dòng)敏感驅(qū)動(dòng)平衡(iMSDE)預(yù)備的平衡穩(wěn)態(tài)自由進(jìn)動(dòng)(bSSFP)序列在糖尿病患者下肢血管成像中的應(yīng)用價(jià)值。方法:這項(xiàng)前瞻性研究招募了35例Ⅱ型糖尿病患者并在1.5TMR掃描儀上先后進(jìn)行NCE-MRA和CE-MRA檢查;獲得的MIP圖像由兩位放射學(xué)醫(yī)師進(jìn)行雙盲評(píng)分并以CE-MRA為參考標(biāo)準(zhǔn)檢測(cè)NCE-MRA對(duì)血管狹窄的診斷精度;兩者間血管診斷價(jià)值血管段比率的比較采用χ~2檢驗(yàn)。結(jié)果:NCE-MRA在盆腔段血管中診斷價(jià)值血管段比率較CE-MRA降低。兩位醫(yī)師對(duì)NCE-MRA組圖像的敏感性、特異性、陽(yáng)性預(yù)測(cè)值、陰性預(yù)測(cè)值以及NCE-MRA準(zhǔn)確率分別為95%/87%、96%/95%、57%/72%、99%/99%、96%/95%(κ=0.76)。結(jié)論:此項(xiàng)基于NCE-MRA技術(shù)的iMSDE預(yù)備的bSSFP序列可有效的顯示糖尿病患者下肢動(dòng)脈病變,并且具備不使用造影劑、掃描時(shí)間短優(yōu)點(diǎn)以及大腿及小腿段血管具備較好的診斷價(jià)值。
[Abstract]:Objective: to evaluate the application value of balanced steady-state free precession (bSSFPFP) sequence prepared by non-contrast enhanced magnetic resonance angiography (NCE-MRA) technique in patients with diabetes mellitus (DM). Methods:. The prospective study recruited 35 patients with type 2 diabetes and performed NCE-MRA and CE-MRA examinations on a 1.5T Mr scanner. The obtained MIP images were scored by two radiologists and the accuracy of NCE-MRA in the diagnosis of vascular stenosis was detected by using CE-MRA as the reference standard. 蠂 ~ 2 test was used to compare the ratio of diagnostic value of vascular segment between the two groups. Results the ratio of diagnostic value of vascular segment in the pelvic segment was lower than that of CE-MRA. The sensitivity, specificity and positive predictive value of the two physicians to the images of the NCE-MRA group were higher than those of the control group. The negative predictive value and the accuracy of NCE-MRA were 95 / 87 and 96 / 95, respectively. They were 57 / 72, and 99 / 99 / 99, 96 / 95, respectively. Conclusion: the bSSFP sequence prepared by iMSDE based on NCE-MRA technology can effectively display arterial lesions in the lower extremities of diabetic patients, and it has no contrast agent. The advantages of short scanning time and the blood vessels of thigh and leg have good diagnostic value.
【作者單位】： 南方醫(yī)科大學(xué)非直屬附屬?gòu)V東省第二人民醫(yī)院影像中心;新疆維吾爾自治區(qū)人民醫(yī)院影像中心;
【基金】：廣東省第二人民醫(yī)院青年基金項(xiàng)目(編號(hào):YQ2015-015)
【分類號(hào)】：R445.2;R587.2

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本文編號(hào)：1630710