【摘要】：目的:觀察益腎利濕化瘀法結(jié)合B超引導(dǎo)下穿刺抽液硬化術(shù)治療單純性腎囊腫的遠(yuǎn)期療效是否優(yōu)于單純穿刺抽液硬化術(shù)。方法:使用隨機(jī)、對(duì)照設(shè)計(jì),對(duì)直徑4cm的單純性腎囊腫進(jìn)行干預(yù)治療,對(duì)比兩組,即B超引導(dǎo)下穿刺抽液硬化術(shù)(對(duì)照組)和加用益腎利濕化瘀法中藥湯劑口服治療28天(治療組),統(tǒng)計(jì)3、6、12個(gè)月后的療效及復(fù)發(fā)率。結(jié)果:腎囊腫穿刺前:治療組(n=27)、對(duì)照組(n=26)囊腫的直徑分別為(6.66土1.90)cm、(6.95±2.10)cm(P0.05),囊腫的體積分別為(129.60±121.50)ml、(144.41±137.94)ml(P0.05);經(jīng)穿刺后,治療組、對(duì)照組囊腫的體積分別為(19.54±10.68)ml、(22.82±9.51)ml(P0.05)。3、6、12個(gè)月后復(fù)查:治療組囊腫的體積為(6.81 土9.41)ml、(6.81±12.05)ml、(7.08±19.54)ml,明顯小于穿刺后的體積(19.54±10.68)ml(P0.05);對(duì)照組 3、6、12 個(gè)月后復(fù)查囊腫體積為(41.07±78.92)ml、(42.83±88.40)ml、(46.85±90.17)ml,與穿刺后的體積(22.82±9.51)ml 存在顯著差異(P0.05);經(jīng)治療12個(gè)月后治療組囊腫直徑為(1.71±1.50)cm,囊腫體積為(7.08±19.54)ml與對(duì)照組囊腫直徑(3.99±2.34)cm,囊腫體積(46.85±90.17)ml相比均存在明顯差異(P0.05);且治療組患者總有效率為96.29%,明顯高于對(duì)照組患者總有效率69.23%(P0.05),說(shuō)明治療組在遠(yuǎn)期療效上明顯優(yōu)于對(duì)照組。在復(fù)發(fā)率方面,治療組(3.70%)較對(duì)照組(37.77%)存在明顯差異(P0.05),表明在中藥干預(yù)治療后單純性腎囊腫遠(yuǎn)期復(fù)發(fā)率明顯降低。在癥狀改善方面,治療組改善率92.86%,對(duì)照組88.89%,兩組在癥狀改善方面均有很好療效。兩者均無(wú)明顯不良反應(yīng)。關(guān)于單純性腎囊腫是否影響腎功能,對(duì)53例患者穿刺前和穿刺后比較后發(fā)現(xiàn),肌酐、尿素氮、尿酸、及收縮壓并無(wú)明顯差異(P0.05)。結(jié)論:采用益腎利濕化瘀法結(jié)合B超穿刺抽液硬化術(shù)其遠(yuǎn)期療效明顯優(yōu)于單純使用穿刺抽液硬化術(shù)治療單純性腎囊腫(直徑4cm者)。
[Abstract]:Objective: to observe whether the long-term effect of invigorating kidney, promoting dampness and removing blood stasis combined with B-ultrasound guided puncture and drainage sclerosis in the treatment of simple renal cysts is better than that of simple puncture and drainage sclerosis. Methods: simple renal cysts with diameter 4cm were treated with random and controlled design. The curative effect and recurrence rate after 12 months of treatment were compared between the two groups, namely, B-ultrasound guided puncture and drainage sclerosis (control group) and oral treatment with Yishen Lishui Huayu decoction for 28 days (treatment group). Results: before puncture of renal cysts: the diameter of cysts in treatment group (n 鈮，

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