【摘要】：目的:探討保留睪丸動脈顯微手術(shù)聯(lián)合服用麒麟丸治療雙側(cè)精索靜脈曲張(VC)合并少弱精子癥的臨床療效。方法:60例雙側(cè)精索靜脈曲張并少弱精子癥患者,隨機分為兩組,單純手術(shù)組30例,顯微手術(shù)聯(lián)合服用麒麟丸組30例,療程12周,每次服用6 g,每日3次,觀察治療后第4、8、12周兩組患者精子濃度、精液量、精子活力(a+b級)、畸形精子百分率、血清Inh B、LH、TT和FSH水平變化,并計算睪酮分泌指數(shù)(TSI=TT/LH)。結(jié)果:患者均手術(shù)成功,術(shù)后癥狀消失,精子濃度、精液量、精子活力明顯提高,畸形精子百分率明顯降低,術(shù)后血清Inh B、TT、TSI明顯改善,FSH、LH含量降低,與術(shù)前比較,差異有統(tǒng)計學意義(P㩳0.01)。手術(shù)聯(lián)合服用麒麟丸組治療12周后血清Inh B、LH、TT及TSI分別為(138.96±22.26)ng/L、(3.17±0.12)IU/L、(13.98±3.02)nmol/L、(4.41±0.53)nmol/IU,單純手術(shù)組治療12周后分別為(129.54±22.23)ng/L、(3.59±0.11)IU/L、(12.68±3.12)nmol/L、(3.53±0.51)nmol/IU,兩組間對比差異有顯著性(P㩳0.05)。手術(shù)聯(lián)合服用麒麟丸組受孕22例,受孕率為73.4%,比單純手術(shù)組受孕11例、受孕率為36.6%效果顯著(P㩳0.05)。結(jié)論:保留睪丸動脈顯微手術(shù)聯(lián)合服用麒麟丸治療雙側(cè)精索靜脈曲張所致少弱精子癥,對于術(shù)后精液質(zhì)量改善明顯、療效滿意。
[Abstract]:Objective: to investigate the clinical effect of testicular artery preserving microsurgery combined with Kirin pill in the treatment of bilateral varicocele (VC) with oligozoospermia. Methods Sixty patients with bilateral varicocele and oligozoospermia were randomly divided into two groups: 30 cases in simple operation group and 30 cases in Kirin pill group. The course of treatment was 12 weeks. The sperm concentration, spermatozoa volume, sperm motility (a b grade), abnormal sperm percentage, serum InhB LHH TT and FSH levels were observed and the testosterone secretion index (TSI TT / LH) was calculated at the 12th week after treatment. Results: all the patients were successfully operated, the symptoms disappeared, the sperm concentration, spermatozoa volume, sperm motility increased, the percentage of abnormal spermatozoa decreased, and the serum Inh Btrot TSI significantly improved the decrease of FSH LH after operation, which was compared with that before operation. The difference was statistically significant (P0. 01). After 12 weeks of treatment, the serum levels of serum Inh Btrope LHHHHNTT and TSI were (138.96 鹵22.26) ng / L, (3.17 鹵0.12) nmol / L, (13.98 鹵3.02) nmol / L, (4.41 鹵0.53) nmol / L respectively in the operation group, and (129.54 鹵22.23) ng / L, (3.59 鹵0.11) nmol / L, (12.68 鹵3.12) nmol / L, (3.53 鹵0.51) nmol / L in the operation group, respectively. The pregnancy rate was 73.4% in the operation combined with Kirin pill group, which was significantly higher than that in the operation group (36.6%) (P 0.05). Conclusion: the treatment of oligozoospermia caused by varicocele by preserving testicular artery microsurgery combined with Kirin pill is satisfactory for the improvement of semen quality after operation.
【作者單位】： 青州市人民醫(yī)院/青島大學醫(yī)療集團青州醫(yī)院泌尿外科;濰坊醫(yī)學院附屬益都中心醫(yī)院中心實驗室;
【分類號】：R699

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