本文選題：等離子切除 + 膀胱腫瘤　； 參考：《重慶醫(yī)科大學(xué)》2014年碩士論文

【摘要】：目的研究與傳統(tǒng)電切（TURBT）治療膀胱腫瘤相比，經(jīng)尿道等離子切除（PKRBT）在臨床使用中的優(yōu)點(diǎn)和缺點(diǎn)，為以后臨床決策及研究提供客觀的依據(jù)。 方法通過(guò)計(jì)算機(jī)檢索1993年-2013年P(guān)ubmed、EMbase、Cochrane圖書(shū)館、CNKI、中國(guó)生物醫(yī)學(xué)文獻(xiàn)數(shù)據(jù)庫(kù)、維普數(shù)據(jù)庫(kù)等，通過(guò)手工檢索輔助完整的收集相關(guān)文獻(xiàn)，搜索內(nèi)容為所有涉及比較經(jīng)尿道等離子切除與傳統(tǒng)電切術(shù)處理膀胱腫瘤的隨機(jī)對(duì)照試驗(yàn)，按照納入與排除標(biāo)準(zhǔn)選擇合適文獻(xiàn)，通過(guò)資料提取和質(zhì)量評(píng)價(jià)后其中7篇符合等離子切除術(shù)與經(jīng)尿道電切術(shù)的隨機(jī)對(duì)照研究（RCTs），，應(yīng)用Reman5.0軟件進(jìn)行數(shù)據(jù)處理和分析。 結(jié)果對(duì)成功納入的符合標(biāo)準(zhǔn)的7篇文獻(xiàn)，統(tǒng)計(jì)共有643例患者，進(jìn)行meta分析后得出結(jié)果如下：1.手術(shù)時(shí)間比較兩組無(wú)明顯差異[WMD=-0.89，95%CI（-2.77，0.99），P=0.35]；2.術(shù)中出血量比較兩組無(wú)明顯差異[WMD=-6.79，95%CI（-16.12，2.55），P=0.15]；3.手術(shù)并發(fā)癥比較等離子切除術(shù)低于傳統(tǒng)經(jīng)尿道電切術(shù)[RR=0.31，95%CI（0.21，0.48），P0.00001]；4.術(shù)后復(fù)發(fā)率等離子切除術(shù)低于傳統(tǒng)經(jīng)尿道電切術(shù)[RR=0.70，95%CI（0.53，0.92），P0.001]。 結(jié)論與傳統(tǒng)經(jīng)尿道電切術(shù)治療淺表性膀胱癌相比，經(jīng)尿道等離子切除術(shù)更安全有效，能降低手術(shù)并發(fā)癥及術(shù)后2年內(nèi)的復(fù)發(fā)率。
[Abstract]:Objective to study the advantages and disadvantages of transurethral resection of PKRBT in the treatment of bladder neoplasms compared with traditional TURBT, and to provide an objective basis for future clinical decision making and research. Methods CNKI, China Biomedical Literature Database and Wiper Database were searched by computer from 1993 to 2013 in the Pubmedus EMbase Cochrane Library. The relevant documents were collected by manual retrieval. All randomized controlled trials involving the comparison of transurethral plasma resection and conventional electroresection of bladder tumors were conducted, and appropriate literature was selected according to the inclusion and exclusion criteria. After data extraction and quality evaluation, seven of them were randomly compared with plasma resection and transurethral resection. The data were processed and analyzed by Reman5.0 software. Results A total of 643 patients were included successfully in 7 articles that met the criteria. The results of meta analysis were as follows: 1. 1. There was no significant difference in operation time between the two groups. There was no significant difference in intraoperative blood loss between the two groups [WMD-6.79N95, CI-16.122.55P0. 15]. Compared with conventional transurethral resection, the complications of operation were lower than that of conventional transurethral resection. The recurrence rate of plasma resection was lower than that of traditional transurethral resection. Conclusion compared with traditional transurethral resection, transurethral plasma resection is more safe and effective in the treatment of superficial bladder cancer, and can reduce the postoperative complications and recurrence rate within 2 years.
【學(xué)位授予單位】：重慶醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2014
【分類號(hào)】：R737.14

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